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Rabbit Anti-ARG2 Polyclonal Antibody#abs140871

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Description

Catalog-specification	Delivery time	USD price
abs140871-100ug	1-2 Weeks	301.0
abs140871-50ug	1-2 Weeks	201.0

Overview
catalog	abs140871
Other names	Arginase II, also known as mitochondrial arginase or kidney-type arginase, is an enzyme that plays an important role in the urea cycle. It is responsible for converting arginine, an amino acid, into ornithine and urea in the mitochondria of cells. This enzyme is expressed in non-hepatic tissues, including the kidney, and is involved in a number of physiological processes such as collagen synthesis, cell proliferation, and regulation of nitric oxide levels. Arginase II is distinct from arginase I, which is primarily found in the liver. This enzyme is a potential target for therapeutic intervention in a variety of diseases including cancer, cardiovascular disease, and neurological disorders.
Source	Rabbit
Specificity	The ARG2 Antibody has the ability to recognize and measure the levels of total ARG2 protein present in the body. This valuable tool is designed to detect endogenous levels of total ARG2, providing researchers with reliable and accurate data for their studies. By utilizing ARG2 Antibody, researchers can gain important insights into the functioning and significance of ARG2 in various biological processes.
Species Reactivity	Human
Antigen	ARG2
Application	： WB（Western blot）1:500~1:1000，IF（）/ICC（）1:100-1:500，ELISA（）（）1:20000-1:40000。，ChapGPT，。
Immunogen	A synthesized peptide.
MW	38 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. The resulting product was highly purified and free of impurities. This method exploits the specific binding affinity between the peptide ligand and the target protein, allowing for efficient and selective purification of the desired protein. The resulting antiserum was suitable for a wide range of applications, including diagnostic, therapeutic, and research purposes. The use of this purification method ensures a highly pure and functional antiserum that is suitable for use in a variety of applications.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain product stability, it is recommended to keep the product stored at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing to prevent any damage or degradation. Make sure to follow these guidelines to ensure that the product remains safe and effective for use.
Storage buffer	This product is Rabbit IgG, supplied in phosphate buffered saline (pH 7.4) with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. The stability of this product is guaranteed for a period of 12 months starting from the date of receipt.
Target
Background	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Tissue specificity	Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
Celluar localization	Mitochondrion;
UniPort	P78540