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Rabbit Anti-APLP2 Polyclonal Antibody#abs140851

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Description

Catalog-specification	Delivery time	USD price
abs140851-100ug	1-2 Weeks	301.0
abs140851-50ug	1-2 Weeks	201.0

Overview
catalog	abs140851
Other names	HSD2, also known as amyloid-beta precursor protein-like protein 2, is a protein that shares similarity with the amyloid precursor protein (APP). It is also referred to as amyloid-like protein 2 or amyloid protein homolog. APLP-2 or Aplp2 is an abbreviation commonly used for this protein. It is also known by its full name, amyloid precursor protein homolog HSD2. Another term associated with HSD2 is CDEBP, which stands for CDEI box binding protein. This protein plays a role in various cellular processes and may have implications in amyloid-related diseases.
Source	Rabbit
Specificity	The APLP2 Antibody has the capability of detecting the entirety of APLP2 levels in the body. It can pick up on these levels even when they are naturally occurring within the system. For this reason, it is a reliable tool for researchers and medical professionals who are looking to study APLP2 and its effects on the body. By detecting the entire APLP2 molecule, this antibody is able to provide a more comprehensive understanding of how APLP2 works in the body.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Horse
Antigen	APLP2
Application	WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	87 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. To ensure the similarity of the generated content, the original text information was rearranged.
Clonality	Polyclonal Antibody
Stability & Storage	The recommended storage condition is at -20 °C for one year without subjecting it to repeated freeze/thaw cycles. It is important to store it properly to maintain its integrity and quality.
Storage buffer	This is the product information for Rabbit IgG: - It is stored at -20 °C. - The solution contains Rabbit IgG in phosphate buffered saline at pH 7.4. - It also contains 150mM NaCl and 0.02% sodium azide. - Additionally, it includes 50% glycerol to preserve the integrity of the antibody. - The product is stable for a period of 12 months starting from the date of receipt.
Target
Background	May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
Tissue specificity	Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Posttranslational modification	The BPTI/Kunitz inhibitor domain is O-glycosylated.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;Nucleus;Plasma Membrane;
UniPort	Q06481