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Rabbit Anti-Ameloblastin Polyclonal Antibody#abs138023

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Description

Catalog-specification	Delivery time	USD price
abs138023-100ug	1-2 Weeks	301.0
abs138023-50ug	1-2 Weeks	201.0

Overview
catalog	abs138023
Other names	AMBN_HUMAN, also known as ameloblastin, is a vital enamel matrix protein that plays a crucial role in enamel formation. This protein is secreted by ameloblasts, which are specialized cells responsible for enamel formation during tooth development. Ameloblastin is essential in regulating the mineralization process, ensuring the proper formation and hardness of tooth enamel. The amino acid sequence of AMBN_HUMAN is highly conserved among various species, indicating its essential role in tooth development and evolution. Mutations in the AMBN_HUMAN gene have been associated with dental anomalies, such as enamel hypoplasia and amelogenesis imperfecta, highlighting the critical role of this protein in maintaining dental health. Overall, AMBN_HUMAN is a vital protein involved in enamel formation and mineralization, and any alterations in its sequence can lead to various dental anomalies, underlining the need for continued research on this protein's function and potential therapeutic applications.
Source	Rabbit
Specificity	The Ameloblastin Antibody can identify total Ameloblastin present within an organism. This detection is based upon the detection of endogenous levels of this molecule.
Species Reactivity	Human
Predictive reaction species	Rabbit
Antigen	Ameloblastin
Application	WB 1:500-2000, ELISA(peptide) 1:20000-1:40000
Immunogen	Ameloblastin, a human-derived protein, has been utilized to produce a synthesized peptide. The newly developed peptide closely resembles the original protein but is rearranged to enhance its properties. This innovative approach utilizes the valuable information embedded in Ameloblastin while creating a distinct and highly similar synthesized peptide. By harnessing the molecular structure and functional characteristics of Ameloblastin, this advanced synthesis technique showcases the potential for tailored peptides with improved performance in various applications.
MW	48 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the item at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the item to multiple freeze/thaw cycles, as this can have a detrimental effect on its stability. Preserve the quality by adhering to these storage instructions.
Storage buffer	This product contains rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To maintain its quality, please store it in a -20 °C temperature. It can last up to 12 months from the date of receipt. If you need a reliable source of rabbit IgG, this product is an excellent choice. Ensure that you follow the recommended storage conditions for the best results.
Target
Background	Involved in the mineralization and structural organization of enamel.
Tissue specificity	Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	Q9NP70