Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-ALS2CR8 Polyclonal Antibody#abs140854

Please note that the price mentioned is only for your reference and for detailed pricing information, we suggest you get in touch with our seller Vecent. We would like to emphasize that the generated content will be highly similar to the original text as we aim to convey the same message....

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs140854-100ug	1-2 Weeks	301.0
abs140854-50ug	1-2 Weeks	201.0

Overview
catalog	abs140854
Other names	Chromosome region candidate 8 in amyotrophic lateral sclerosis 2 (juvenile), also known as ALS2CR8, is a protein encoded by the Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8. It is also referred to as calcium response factor or calcium-responsive transcription factor (CaRF). Another name for this protein is Testis development protein NYD SP24 or Testis development protein NYD-SP24. These different names are used to describe the same protein with various functions and roles. ALS2CR8 is believed to have an important role in the development and function of the nervous system, specifically in regulating calcium signaling. Calcium response factors are responsible for coordinating cellular responses to changes in calcium levels, which are critical for various physiological processes. The exact mechanisms by which ALS2CR8 functions in calcium signaling and its potential association with amyotrophic lateral sclerosis are still being studied. Furthermore, Testis development protein NYD SP24, or NYD-SP24, suggests a role in the development of the male reproductive system, particularly in the testes. Additional research is needed to determine the precise function of NYD-SP24 and its potential implications for testis development and function. In conclusion, ALS2CR8, calcium response factor or calcium-responsive transcription factor (CaRF), and Testis development protein NYD SP24 (NYD-SP24) are all names used to refer to the same protein encoded by the Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8. These proteins are involved in various biological processes, including calcium signaling and testis development, and may have implications for neurological disorders and reproductive health.
Source	Rabbit
Specificity	The ALS2CR8 Antibody is designed to detect the total amount of ALS2CR8 present naturally within the body. This detection method can accurately measure the endogenous levels of ALS2CR8, making it a reliable tool for researchers and clinicians alike. By detecting the natural levels of ALS2CR8, this antibody can provide valuable insights into the role of ALS2CR8 in various physiological and pathological processes.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit;Chicken;Dog;Horse;
Antigen	ALS2CR8
Application	For Western Blotting (WB), we recommend dilution ratios from 1:500 to 1:1000. When using Immunohistochemistry (IHC), we suggest dilution ratios ranging from 1:50 to 1:200. For Immunofluorescence (IF/ICC), we recommend dilution ratios between 1:100 and 1:500. For ELISA using a peptide, we suggest dilution ratios from 1:20000 to 1:40000. These are ideal dilution ratios to ensure accurate and reliable results when using our products.
Immunogen	A synthesized peptide.
MW	85 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography for purification purposes. A highly similar content could be: Through peptide affinity chromatography with SulfoLink™ Coupling Resin, the antiserum was purified.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimum conditions, it is recommended to store the item at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the item to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Celluar localization	Nucleus;
UniPort	Q8N187