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Rabbit Anti-ALDOB Polyclonal Antibody#abs141143

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Description

Catalog-specification	Delivery time	USD price
abs141143-100ug	1-2 Weeks	301.0
abs141143-50ug	1-2 Weeks	201.0

Overview
catalog	abs141143
Other names	Aldolase B, also known as ALDB or ALDOB, is an enzyme that plays a crucial role in the breakdown of carbohydrates in the body. It is a liver-specific isoform of the aldolase enzyme, which is involved in the conversion of fructose into other forms of energy. Aldolase B catalyzes the conversion of fructose-1,6-bisphosphate to two three-carbon molecules that can be used for energy production. The gene that encodes for aldolase B is located on chromosome 9, and mutations in this gene can lead to hereditary fructose intolerance, a rare genetic disorder that affects the liver's ability to process fructose. Aldolase B is also found in a variety of other tissues, including the kidney, intestine, and brain, where it plays a role in glucose metabolism. Its structure and function have been extensively studied, and this enzyme is considered a vital component of carbohydrate metabolism in the body.
Source	Rabbit
Specificity	The ALDOB Antibody is capable of detecting the total ALDOB protein at its natural levels within an organism. To emphasize, this antibody specifically targets and recognizes endogenous levels of ALDOB.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit
Antigen	ALDOB
Application	WB 1:500~1:1000，IF/ICC 1:100-1:500，ELISA（）1:20000-1:40000。。，。，。
Immunogen	A synthesized peptide.
MW	39 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography was used to purify the antiserum, with SulfoLink™ Coupling Resin employed for the process.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at -20 °C for a duration of one year, while being cautious to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	The recommended storage conditions for Rabbit IgG include storing it at -20 °C in a solution of phosphate buffered saline with a pH of 7.4. The solution should also contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is advised to use the product within 12 months from the date of receipt to ensure its stability and efficacy.
Target
Background	In vertebrates, 3 forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.
Celluar localization	Cytoskeleton;Cytosol;Extracellular region or secreted;
UniPort	P05062