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Rabbit Anti-ACOX3 Polyclonal Antibody#abs138675

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Description

Catalog-specification	Delivery time	USD price
abs138675-100ug	1-2 Weeks	301.0
abs138675-50ug	1-2 Weeks	201.0

Overview
catalog	abs138675
Other names	Peroxisomes are organelles responsible for various metabolic functions, including the breakdown of fatty acids. One important enzyme found in peroxisomes is acyl-CoA oxidase 3, pristanoyl (ACOX3), which is involved in the breakdown of branched-chain fatty acids known as pristanic acids. ACOX3 is also known as acyl-CoA oxidase, pristanoyl, peroxisomal, and pristanoyl-CoA oxidase. This enzyme plays a crucial role in fatty acid metabolism, as it facilitates the conversion of pristanoyl-CoA into 2-trans, 4-cis-dienoyl-CoA, which can then be further metabolized by other enzymes in the peroxisome. Mutations in the ACOX3 gene have been associated with various metabolic disorders, including peroxisomal biogenesis disorders and Zellweger syndrome. Overall, the function of ACOX3 highlights the importance of peroxisomes in maintaining cellular homeostasis and underscores the complex nature of lipid metabolism in the body.
Source	Rabbit
Specificity	The endogenous levels of total ACOX3 can be detected using the ACOX3 Antibody. This antibody is designed to specifically recognize and bind to the total ACOX3 protein present in the organism. By detecting the levels of ACOX3, researchers can gain insights into its abundance and potential role in various cellular processes.
Species Reactivity	Human
Predictive reaction species	Zebrafish;Xenopus;Sheep;Horse;Bovine
Antigen	ACOX3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ACOX3.
MW	78kda
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography utilizing SulfoLink™ Coupling Resin was utilized to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	It is recommended to store at -20 °C for a year to maintain the quality. Make sure to avoid subjecting to repeated freeze/thaw cycles.
Storage buffer	The recommended storage condition for Rabbit IgG is -20 °C. It should be stored in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the antibody for up to 12 months from the date of receipt.
Target
Background	Oxidizes the CoA-esters of 2-methyl-branched fatty acids.
Celluar localization	Mitochondrion;Peroxisome;
UniPort	O15254