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Rabbit Anti-ACOX2 Polyclonal Antibody#abs138674

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Description

Catalog-specification	Delivery time	USD price
abs138674-100ug	1-2 Weeks	301.0
abs138674-50ug	1-2 Weeks	201.0

Overview
catalog	abs138674
Other names	Acyl CoA oxidase 2, also known as ACOX2 or peroxisomal acyl-coenzyme A oxidase 2, is an enzyme involved in the metabolism of fatty acids. It is responsible for the oxidation of 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA, converting it to 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase or 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase. Another name for this enzyme is trihydroxycoprostanoyl-CoA oxidase. ACOX2 plays a role in the breakdown of branched chain acyl CoA molecules. It is found in peroxisomes and is essential for the proper functioning of these cell organelles. ACOX2 is an important enzyme in lipid metabolism and its dysfunction can lead to metabolic disorders.
Source	Rabbit
Specificity	The ACOX2 Antibody is capable of detecting total ACOX2 levels naturally present within the body. It is a highly effective tool for researchers who wish to study this particular protein and its associated functions. By using this antibody, researchers can gain a deeper understanding of ACOX2 and how it impacts various biological processes. With its ability to accurately detect endogenous ACOX2 levels, this antibody is an essential tool for any scientist working in the field of molecular biology.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep;Bovine;
Antigen	ACOX2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ACOX2.
MW	77 kDa
Properties
Concentration	1mg/ml
purification	By using SulfoLink™ Coupling Resin, the antiserum was subjected to purification via peptide affinity chromatography. A highly effective and efficient method, peptide affinity chromatography was utilized to ensure optimal purification of the antiserum. SulfoLink™ Coupling Resin facilitated the purification process by providing a highly specific and selective approach to identifying and isolating the target peptides. Overall, the antiserum was purified to the highest degree possible, yielding a product that is of optimal quality and performance.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.
Tissue specificity	Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
Celluar localization	Mitochondrion;Peroxisome;
UniPort	Q99424