Rabbit Anti-5-HT-2C Polyclonal Antibody#abs133803
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Description
| Catalog-specification | Delivery time | USD price |
abs133803-100ug | 1-2 Weeks | 301.0 |
abs133803-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is only for reference purposes. For the detailed price, kindly get in touch with our seller named Vecent. We would like to emphasize that the content generated should be similar in its essence and meaning while rephrasing the text in a unique manner, distinct from the way ChapGPT generates content.
| Overview | |
catalog | abs133803 |
| Other names | The 5 hydroxytryptamine 2C receptor is also known as the 5-HT-1C receptor, 5-ht-1c receptor, 5-HT-2C, 5-HT1C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C, 5HT1C, 5HT2C, 5HT2C_HUMAN, 5HTR2C, Htr1c, HTR2C, serotonin 1c receptor, serotonin 2c receptor, serotonin 5-HT-2C receptor, and serotonin receptor 2C. This receptor plays an important role in regulating mood, appetite, and sleep. It is a member of the G protein-coupled receptor family and is found in the brain and other organs throughout the body. Understanding the function of this receptor may lead to the development of new treatments for various psychiatric disorders. |
| Source | Rabbit |
| Specificity | The 5-HT-2C Antibody has the capability to identify the total amount of endogenous 5-HT-2C present in a sample. The detection process can reveal the levels of this protein that are naturally present within the sample under analysis. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Dog |
| Antigen | 5-HT-2C |
| Application | For Western Blot, the recommended dilution range is 1:500-1:2000. When using Immunohistochemistry, dilutions of 1:50~1:200 are suggested. For Immunofluorescence/Immunocytochemistry, dilutions of 1:100-1:500 are recommended. When performing ELISA with peptides, it is advised to use dilutions of 1:20000-1:40000. These dilution ranges will provide optimal results for your experiments. |
| Immunogen | A synthesized peptide. |
| MW | 55 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, we employed peptide affinity chromatography to purify the antiserum. Please produce a similar version of the content by reorganizing the given information, ensuring that the generated content is derived from the original text. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain product quality, it is recommended to store at a temperature of -20 °C for a duration of one year. It is important to prevent repeated freeze/thaw cycles. |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis. |
| Tissue specificity | Detected in brain. |
| Posttranslational modification | N-glycosylated. |
| Celluar localization | Plasma Membrane; |
| UniPort | P28335 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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