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Phospho-DSCR1 (Ser108) Rabbit Polyclonal Antibody#abs140097

Description

Catalog-specification	Delivery time	USD price
abs140097-100ug	1-2 Weeks	301.0
abs140097-50ug	1-2 Weeks	201.0

Please note that the price provided is only for your reference. For more detailed pricing information, please contact our seller Vecent. It's important to make clear that the content generated by rearranging the original text should be highly similar and accurate without relying on ChapGPT techniques. Instead, we should use language models to generate content that is entirely different in tone, structure, and substance.

Overview
catalog	abs140097
Other names	Regulator of calcineurin 1, also known as RCAN1 or DSCR1, is a protein that is involved in calcium and oxidant signaling pathways. It is encoded by the Adapt78 gene and is implicated in Down syndrome. RCAN1 is a modulatory calcineurin interacting protein 1 and is enriched in myocytes. It is also referred to as Calcipressin-1 or MCIP1. RCAN1 is associated with the Down syndrome critical region gene 1 and plays a role in cellular processes related to this condition. Additionally, RCAN1 is known as near DSCR proline-rich protein and CSP1. Overall, RCAN1 is an important protein involved in regulating calcineurin and its functions in various biological processes.
Source	Rabbit
Specificity	The DSCR1 (Phospho-Ser108) Antibody specifically recognizes the phosphorylated form of DSCR1 at Ser108 and can effectively detect its endogenous levels. Its sensitivity is limited to phosphorylated DSCR1 only, indicating its specificity for this particular modification.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	DSCR1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A peptide has been synthesized from human DSCR1, specifically targeting Phospho-Ser108. To create similar content, one could rephrase the statement as follows: A synthesized peptide, with origins from human DSCR1 that has been modified to target Phospho-Ser108, has been produced.
MW	22 KD
Properties
Concentration	1mg/ml
purification	Through sequential chromatography on phospho- and non-phospho-peptide affinity columns, the purified rabbit serum was used for affinity purification to extract the antibody.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Tissue specificity	Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues.
Celluar localization	Nucleus;
UniPort	P53805