HK1 Polyclonal Antibody #abs115378

abs115378-50ul

In Stock

228

Other names

hexokinase;HK;HK1-ta;HK1-tb;HK1-tc;HKD;HKI;HMSNR;HXK1;RP79;HK1-ta;HK1-tb;HK1-tc;HKD;HKI;HMSNR;HXK1

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:2000
IF 1:50 - 1:200

Immunogen

HK1（NP_000179.2）20-300。，。

Properties

Jurkat, THP-1, MCF-7, NIH/3T3, K-562, 293T, and mouse skeletal muscle are all cell lines commonly used in medical research. These cell lines are used to study the behavior of different types of cells and to better understand diseases such as cancer, HIV, and leukemia. Each of these cell lines has unique characteristics that make them suitable for specific types of research.
For example, MCF-7 cells are often used to study breast cancer, while THP-1 cells are used to study inflammation and immune responses. 293T cells are commonly used in gene therapy research, while NIH/3T3 cells are used to study cell signaling pathways. K-562 cells are used to study leukemia and the effects of chemotherapy, while mouse skeletal muscle cells are used to study muscle biology and regeneration.
Despite their differences, these cell lines share many similarities, such as their ability to undergo mitosis and their sensitivity to different types of stimuli. Understanding the properties and behavior of these cell lines is essential for developing new treatments and therapies for a wide range of diseases and conditions.

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
A solution that is commonly used for biological experiments is PBS with 0.02% sodium azide, 50% glycerol, and a pH of 7.3. This buffered solution has a high level of stability and is commonly used to preserve samples for further analysis. The sodium azide acts as a preservative, preventing microbial growth, while the glycerol helps to prevent sample freezing and thawing. Overall, this solution is an ideal choice for researchers who want to ensure the integrity of their samples.

Target

Background

Hexokinases are enzymes that carry out the phosphorylation of glucose, initiating glucose metabolism pathways. This particular gene encodes a version of hexokinase that is found in various tissues and is specifically located on the outer membrane of mitochondria. Mutations in this gene have been linked to hemolytic anemia, which is caused by a deficiency in hexokinase activity. Through alternative splicing, different isoforms of this gene are produced, some of which are specific to certain tissues.

Celluar localization

Mitochondrion outer membrane

UniPort

P19367