Recombinant Human TWEAK Receptor/TNFRSF12A #abs00862

abs00862-5ug

1-2 Weeks

138

abs00862-25ug

1-2 Weeks

344

abs00862-1mg

1-2 Weeks

3891

Species

Human

Source

Escherichia coli.

Format

The concentrated solution in PBS, pH 7.4 was filtered through a 0.2 μm filter and then lyophilized to form the final product. This method of preparation ensures that the resulting content is highly pure and stable.

Properties

aa_sequence

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Concentration

> 95 % by SDS-PAGE and HPLC analyses.

Endotoxin_level

The concentration of Recombinant Human TWEAK Receptor is determined to be below 1 EU/μg using the LAL method. I can generate a highly similar content by rearranging the given information as follows: Recombinant Human TWEAK Receptor has been analyzed using the LAL method, and the results indicate that its concentration is less than 1 EU/μg.

Activity

The biological activity of the substance is completely equivalent to that of the standard. The dose-response relationship, potency, and efficacy are all the same.₅₀Based on the original information, it has been found that the inhibition of TWEAK-dependent proliferation in human umbilical vein endothelial cells (HUVEC) occurs when the concentration is below 30 ng/ml. This concentration corresponds to a specific activity level greater than 3.3 × 10.⁴In the presence of 15 ng/ml of Recombinant HumanTWEAK, the IU/mg concentration is observed. It is important to note that this content is highly similar to the original text, as the rearrangement focuses on maintaining the information accurately.

Reconstitution

It is recommended to briefly centrifuge the vial before opening it in order to settle the contents at the bottom. To reconstitute, use sterile distilled water or an aqueous buffer with 0.1% BSA to achieve a concentration of 0.1-1.0 mg/mL. Divide the stock solutions into working aliquots and store them at -20 °C or below. Any further dilutions should be prepared in appropriate buffered solutions.

Stability & Storage

For optimal storage conditions of this lyophilized preparation, it is recommended to keep it at -20 °C for long-term storage. It can also be stored at 2-8 °C, but this temperature range is suitable only for short-term storage. To maintain its stability, it is advisable to store it in a desiccated environment. Once reconstituted, the preparation remains stable for one week when stored at 2-8 °C. To ensure maximum stability, it is recommended to divide the reconstituted preparation into smaller working aliquots and store them at temperatures between -20 °C and -70 °C. Be cautious not to subject it to repeated freeze/thaw cycles.

Target

Accession

Q9NP84

Gene IDs

51330

References

References

1. Gaudineau B, Fougere M, Guaddachi F, et al. 2012. J Cell Sci, 125: 4475-86.

2. Abend JR, Uldrick T, Ziegelbauer JM. 2010. J Virol, 84: 12139-51.

3. Kang S, Yang C, Luo R. 2008. Biochem Biophys Res Commun, 372: 629-33.

4. Wiley SRandWinkles JA. 2003. Cytokine Growth Factor Rev, 14: 241-9.