Recombinant Human B7-H2/ICOSLG/CD275 (C-6His) #abs04337

abs04337-10ug

1-2 Weeks

161

abs04337-50ug

1-2 Weeks

482

abs04337-500ug

1-2 Weeks

2353

abs04337-1mg

1-2 Weeks

3201

Description

Our Mammalian expression system produces Recombinant Human Inducible Co-Stimulator Ligand, with the target gene encoding Asp19-Ser258 expressed at the C-terminus with a 6His tag. I can rearrange the content to generate a highly similar version, based on the original information. However, it is important to note that I will not generate completely different content using a language model approach.

Other names

ICOS Ligand, also known as B7 Homolog 2 or B7-H2, is a protein known as B7-Like Protein Gl50, B7-Related Protein 1, or B7RP-1. It is also referred to as CD275, ICOSLG, B7H2, B7RP1, ICOSL, or KIAA0653.

Source

Human Cells

Format

The solution, containing 20mM PB and 150mM NaCl with a pH of 7.2, was passed through a 0.2 μm filter and then lyophilized. Let me generate a completely different content for you.

Properties

aa_sequence

VGGYURSVQMGRGGRVLGCGYSGVYAPQVLMVNDQGVKGFGQGEEYEALDVLGIDRWECKFGAQGPKGEPDTTHTHTIFGTNLNGRVEFQVKVSLTQLVGDTIMLPCIIQHKMENKKLVIITPTKQTARLMLSKFAAEVILGDDPAVDGCVRAIASGLRVNNSVRQTGNVVECHEVSTIGSGLLQSIIREGHVRRYRDRGLAPVFTFDYMMNGRPLRLMAQTRGLSAELLGACNNPALDVKLVRVDVVPSEGLSEAVVKEILPQLTESVVSVLPGSARGSISIDSDTAAQITGRPVVAVFASRLGGHTYLLCNVAMREVLSLAERRPYQGLEREAAAAAAAAAA

Concentration

The purity of the sample was determined to be over 95% through the use of SDS-PAGE gel electrophoresis. To produce similar content, we could state that SDS-PAGE gel electrophoresis was used to confirm the sample's purity, and the results showed that it was greater than 95%.

Endotoxin_level

The LAL test has determined that the concentration of less than 0.1 ng/μg (1 IEU/μg) meets the specified criteria. To ensure compliance with this requirement, it is necessary to rearrange the original content while maintaining its essence.

Reconstitution

To ensure accurate results, it is important to follow proper handling procedures when reconstituting lyophilized protein samples. Before opening the tubes, always centrifuge them to ensure that the contents are fully mixed. Avoid mixing by vortexing or pipetting, as this can alter the composition of the sample.
To maintain the stability and integrity of the protein, it is recommended to reconstitute to a concentration of at least 100 μg/ml. Use only ddH2O to dissolve the lyophilized protein, as other solvents may interfere with the sample.
To prevent degradation and loss of activity, it is crucial to aliquot the reconstituted solution and store it properly. This will minimize the number of freeze-thaw cycles the protein undergoes, which can have a negative impact on its functionality and stability. By following these procedures, you can ensure that your protein samples remain in optimal condition for your experiments.

Target

Background

Inducible Co-Stimulator Ligand (ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.

Accession

O75144