WNT4 Polyclonal Antibody #abs118135

abs118135-50ul

In Stock

228

Other names

SERKAL;WNT-4

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:2000

Immunogen

A fusion protein that has been created using recombinant technology is now available. This protein contains a specific sequence that corresponds to amino acids 122-351 of the human WNT4 protein (NP_110388.2). This sequence has been carefully engineered to ensure maximum similarity to the original protein and to preserve its important biological functions. With this fusion protein, researchers and scientists now have a powerful tool in their arsenal for studying WNT4 and its role in human physiology and disease.

Properties

A-549,MCF7

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
The buffer solution contains PBS and 0.02% sodium azide with a pH of 7.3. Additionally, it has 50% glycerol to facilitate its usage. Sodium azide, in this solution, is used as a preservative to prevent the growth of microorganisms. The pH value is important for maintaining the stability and proper functioning of biological substances. Overall, this buffer solution is suitable for various experiments in biology and biochemistry.

Target

Background

The WNT gene family is comprised of genes encoding signaling proteins, linked to important developmental processes and oncogenesis. One of these genes, which shares strong similarities to the Wnt4 protein in mice and rats, has been shown to influence the sex-determination cascade. Through its protein product, this gene coordinates with a nuclear receptor, responsible for preventing testes formation and promoting female development. Additionally, this gene, as well as two other family members, WNT2 and WNT7B, appear to be associated with abnormal proliferation in breast tissue. Mutations in this gene have been linked to SERKAL syndrome and Rokitansky-Kuster-Hauser syndrome.

Celluar localization

Secreted,extracellular matrix,extracellular space

UniPort

P56705