TNRC6A Polyclonal Antibody #abs116975

abs116975-50ul

In Stock

228

Other names

CAGH26;GW1;GW182;TNRC6

Source

Rabbit

Species Reactivity

Human;Mouse;Rat

Application

WB 1:500 - 1:1000
IF 1:50 - 1:100

Immunogen

A peptide that has been synthesized to match a specific sequence found within human TNRC6A, which consists of amino acids ranging from 950 to 1050, has been created. This synthetic peptide was designed to closely resemble the original sequence found within the protein NP_055309.2.

Properties

Mouse brain,Rat brain

Properties

Purification

Affinity purification

Clonality

Polyclonal Antibody

Isotype

IgG

Stability & Storage

Store at -20℃. Avoid freeze / thaw cycles.

Storage buffer

Store at -20℃. Avoid freeze / thaw cycles.
To prepare the buffer PBS, we need to add 0.02% of sodium azide and 50% of glycerol to the solution. The pH level should be adjusted to 7.3. This buffer solution can be stored with the addition of sodium azide for preservation. The glycerol will also assist in the long-term storage of the buffer solution. The pH level of 7.3 is ideal for the biological processes that will be carried out with this buffer solution. Therefore, it is essential to ensure that the buffer PBS is prepared correctly to avoid any disruptions during the experimental procedures.

Target

Background

This particular genetic sequence is responsible for encoding a member of the protein family called trinucleotide repeat containing 6. The main role of this protein is to participate in post-transcriptional gene silencing by engaging in the processes of RNA interference (RNAi) and microRNA pathways. Within the cytoplasm, it forms connections with messenger RNAs and Argonaute proteins, primarily within specialized organelles called GW-bodies or P-bodies. If the expression of this gene is inhibited, it disrupts the localization of other proteins within GW-bodies and hampers the effectiveness of RNAi and microRNA-induced gene silencing.

Celluar localization

Cytoplasm,P-body

UniPort

Q8NDV7