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TCF4 Polyclonal Antibody #abs115428

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Description

Catalog-specification	Delivery time	USD price
abs115428-50ul	In Stock	228

Overview
Other names	bHLHb19;E2-2;FECD3;ITF-2;ITF2;PTHS;SEF-2;SEF2;SEF2-1;SEF2-1A;SEF2-1B;SEF2-1D;TCF-4
Source	Rabbit
Species Reactivity	Human,Mouse,Rat
Application	WB 1:500 - 1:2000 IF 1:50 - 1:200
Immunogen	A fusion protein made by combining different sequences contains a portion that corresponds to amino acids 400-500 of TCF4 in humans (NP_001077431.1). It is important to ensure that any generated content is closely based on the original text for accuracy and consistency.
Properties	A-375,K-562
Properties
Purification	Affinity purification
Isotype	IgG
Stability & Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. This solution contains PBS mixed with 0.02% sodium azide and 50% glycerol, with a pH of 7.3. The final solution is preserved with sodium azide and glycerol to maintain its stability and pH.
Target
Background	Transcription factor 4, a basic helix-loop-helix transcription factor, is encoded by this gene. It exhibits a broad expression pattern and is involved in nervous system development. This protein specifically recognizes the Ephrussi-box binding site, known as the 'CANNTG' motif, which was first identified in immunoglobulin enhancers. Pitt-Hopkins syndrome is a disorder that can arise from defects in this gene. Another condition, Fuchs endothelial corneal dystrophy, can occur when an intronic CTG repeat, usually consisting of 10-37 repeat units, expands to over 50 repeat units. Interestingly, multiple alternative splicing events give rise to distinct protein isoforms encoded by this gene.
Celluar localization	Nucleus
UniPort	P15884