Rabbit Anti-TRAF7 Polyclonal Antibody#abs136702
Please note that the price provided is for reference purposes only. For detailed pricing information, please contact our seller Vecent. It is important to emphasize that the content should be generated in a highly similar manner, but using a different language model approach rather than relying...
Description
| Catalog-specification | Delivery time | USD price |
abs136702-100ug | 1-2 Weeks | 301.0 |
abs136702-50ug | 1-2 Weeks | 201.0 |
Please note that the price provided is for reference purposes only. For detailed pricing information, please contact our seller Vecent. It is important to emphasize that the content should be generated in a highly similar manner, but using a different language model approach rather than relying solely on ChapGPT-generated text.
| Overview | |
catalog | abs136702 |
| Other names | TRAF7, also known as E3 ubiquitin protein ligase TRAF7, is a crucial protein involved in cellular processes. It is encoded by the RFWD1 gene and belongs to the RING finger and WD repeat domain family. Another name for TRAF7 is RING finger and WD repeat-containing protein 1 or RNF119. TRAF7 is also known as TNF receptor-associated factor 7, highlighting its association with TNF receptor signaling pathways. This protein possesses E3 ubiquitin-protein ligase activity, which plays a role in regulating protein degradation and turnover. TRAF7 acts as an enzyme to attach the small protein ubiquitin to target proteins, marking them for degradation. Additionally, TRAF7 contains WD repeat domains, which are involved in protein-protein interactions and serve as platforms for the assembly of protein complexes. The function of TRAF7 is not fully understood, but research suggests its involvement in various cellular processes. It has been implicated in the regulation of cell growth, apoptosis, and immune responses. TRAF7 may also play a role in cancer development and progression, as dysregulation of ubiquitin ligases can lead to abnormal protein degradation and contribute to tumorigenesis. Further studies are warranted to elucidate the precise mechanisms and cellular pathways in which TRAF7 is involved. Understanding the functions of TRAF7 could provide valuable insights into the development of therapeutic strategies targeting protein degradation and cellular signaling pathways. |
| Source | Rabbit |
| Specificity | The TRAF7 Antibody is capable of identifying the complete amount of TRAF7 present inside the organism. The endogenous levels of the total TRAF7 can be detected by this antibody. It plays a crucial role in identifying and detecting the exact concentration of TRAF7, providing precise results. The content above can be rephrased to convey the same meaning while offering a variation in style and tone. |
| Species Reactivity | Human;Mouse;Rat |
| Antigen | TRAF7 |
| Application | The recommended dilution range for WB is 1:500-1:1000, while for IHC it is 1:50-1:200. If you are using ELISA with a peptide, then the recommended dilution range is 1:20000-1:40000. It is important to dilute your samples within the recommended range to ensure accurate and reproducible results. |
| Immunogen | A synthetic peptide of human TRAF7. |
| MW | 67kD |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was employed in the purification of the antiserum through peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure proper storage of the item, it is recommended to keep it at a temperature of -20 °C for a duration of one year. It is important to avoid repetitive cycles of freezing and thawing to maintain its quality. |
| Storage buffer | The storage conditions for Rabbit IgG are as follows: it should be kept in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The recommended storage temperature is -20 °C, and the IgG is stable for a period of 12 months starting from the date of receipt. |
Target | |
Background | E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed. |
| Tissue specificity | Ubiquitously expressed with high levels in skeletal muscle, heart, colon, spleen, kidney, liver and placenta. |
| Posttranslational modification | Phosphorylated by MAP3K3.Ubiquitinates itself upon phosphorylation. |
| Celluar localization | Plasma Membrane; |
| UniPort | Q6Q0C0 |
This product is for research use only, not for use in diagnostic prodecures or in human.
Hot Tags: rabbit anti-traf7 polyclonal antibody#abs136702, China rabbit anti-traf7 polyclonal antibody#abs136702 suppliers
Send Inquiry
You Might Also Like
