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Rabbit Anti-TBX15/18 Polyclonal Antibody#abs138247

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Description

Catalog-specification	Delivery time	USD price
abs138247-100ug	1-2 Weeks	301.0
abs138247-50ug	1-2 Weeks	201.0

Overview
catalog	abs138247
Other names	The T-box family of proteins plays an important role in regulating gene expression during embryonic development and tissue differentiation. Two key members of this family are T-box protein 18 (TBX18) and T-box protein 15 (TBX15). TBX18 is a transcription factor that is involved in the development of the heart, urinary tract, and other tissues, while TBX15 is involved in the development of skeletal muscle and bone. In addition to these two main proteins, there are also several related proteins, including TBX14 and TBX8. These proteins share many similarities with TBX18 and TBX15 and may have overlapping functions in development. Overall, the T-box family of proteins is crucial for proper embryonic development and tissue differentiation, and understanding their roles and relationships is important for understanding the underlying mechanisms of these processes.
Source	Rabbit
Specificity	The endogenous levels of total TBX15/18 can be accurately identified using the TBX15/18 Antibody. This antibody specifically detects the presence of TBX15/18 and can be used to measure their levels in biological samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	TBX15/18
Application	IHC 1:200, WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500. These are the recommended dilutions for different immunological techniques. For Western blotting (WB), the recommended dilutions range from 1:1000 to 1:3000. Immunohistochemistry (IHC) typically requires a dilution of 1:200. For immunofluorescence/immunocytochemistry (IF/ICC), the suggested dilutions are between 1:100 and 1:500. Lastly, for ELISA using peptide antigens, the appropriate dilutions are 1:20000-1:40000.
Immunogen	A synthesized peptide derived from human TBX15/18.
MW	65 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was used to purify the antiserum via peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of your product, it is recommended to store it at a temperature of -20 °C for up to one year. However, it is important to note that repeated freeze/thaw cycles could negatively impact the quality of the product. Therefore, it is best to avoid such cycles as much as possible. By following these guidelines, you can guarantee that your product will remain in top condition for as long as possible.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.
Celluar localization	Nucleus;
UniPort	O95935/Q96SF7