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Rabbit Anti-PODXL2 Polyclonal Antibody#abs139691

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Description

Catalog-specification	Delivery time	USD price
abs139691-100ug	1-2 Weeks	301.0
abs139691-50ug	1-2 Weeks	201.0

Overview
catalog	abs139691
Other names	Here's a new version: The gene with the identifier OTTHUMP00000216064, also known as PODLX2, encodes for a protein called podocalyxin like 2, or PODXL2 for short. This protein is similar in structure to podocalyxin, another protein with important roles in cell adhesion and migration. However, the exact functions of PODXL2 are still being studied and its potential as a therapeutic target for disease remains to be explored.
Source	Rabbit
Specificity	The PODXL2 Antibody is capable of detecting total endogenous levels of PODXL2 protein. To ensure accurate detection, this antibody has been designed to specifically target PODXL2 protein and can detect both its active and inactive forms. By utilizing this antibody, researchers can easily monitor the expression and regulation of PODXL2 in various biological samples.
Species Reactivity	Human
Predictive reaction species	Pig;Bovine;Dog
Antigen	PODXL2
Application	，：ELISA ()1:20000-1:40000，IF/ICC1:100-1:500，WB1:1000-3000。，，。
Immunogen	A synthesized peptide derived from human PODXL2.
MW	65 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography. A highly similar content can be generated by rearranging the original text information in a different way.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is essential to avoid exposing the product to repetitive cycles of freezing and thawing, as this can negatively impact its integrity. Taking these precautions will ensure that the product maintains its optimal quality and efficacy.
Storage buffer	This product contains rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4. It also includes 150mM NaCl, 0.02% sodium azide and 50% glycerol, and should be stored at -20 °C. The product is stable for 12 months from the date of receipt.
Target
Background	Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins.
Tissue specificity	Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells.
Posttranslational modification	Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides.Sulfation is necessary for interaction with SELL. Sialylated O-linked oligosaccharides are necessary for interaction with SELL, SELE and SELP.
Celluar localization	Golgi apparatus;Plasma Membrane;
UniPort	Q9NZ53