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Rabbit Anti-TAT Polyclonal Antibody#abs137946

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Description

Catalog-specification	Delivery time	USD price
abs137946-100ug	1-2 Weeks	301.0
abs137946-50ug	1-2 Weeks	201.0

Overview
catalog	abs137946
Other names	TAT, also known as L-tyrosine:2-oxoglutarate aminotransferase, or tyrosine aminotransferase, is an important enzyme found in the cytosol. Its main function is to catalyze the transfer of amino groups from L-tyrosine to 2-oxoglutarate, resulting in the formation of L-glutamate and 4-hydroxyphenylpyruvate. This process is vital for the biosynthesis of important compounds such as dopamine, epinephrine and norepinephrine, making TAT a crucial component in several metabolic pathways. The cytosolic location of TAT also plays a significant role in its function, as it ensures that it interacts efficiently with other enzymes involved in the same pathways. Overall, TAT is an essential enzyme with important regulatory functions in several cellular processes involved in maintaining physiological homeostasis.
Source	Rabbit
Specificity	The TAT Antibody is capable of identifying the total TAT protein in its natural state. To create similar content by reorganizing the provided information, the text could read: The detection abilities of the TAT Antibody extend to the endogenous levels of total TAT, allowing it to identify this protein in its unaltered form.
Species Reactivity	Human;Mouse
Antigen	TAT
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TAT.
MW	140 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification process for the antiserum was carried out through peptide affinity chromatography. To achieve a highly purified antiserum, this method was employed to effectively isolate and extract the desired peptide from the serum. By utilizing the SulfoLink™ Coupling Resin, efficiency was increased, thereby resulting in a more successful and reliable purification process.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at a temperature of -20 °C for a period of one year and remember to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	This solution contains Rabbit IgG of high purity, dissolved in a buffer of phosphate buffered saline at a pH of 7.4, with 150mM NaCl, 0.02% sodium azide and 50% glycerol for stability. It should be stored at -20 °C. The solution will remain stable for up to 12 months from the date of receipt. This product is ideal for use in a variety of applications, including immunoblotting, immunoprecipitation, and ELISA. Its high purity ensures minimal background interference and excellent sensitivity, making it an essential tool for many research projects.
Target
Background	This enzyme is involved in the breakdown of tyrosine and is known as a transaminase. It converts tyrosine into p-hydroxyphenylpyruvate. Interestingly, it can also catalyze the reverse reaction using glutamic acid and 2-oxoglutarate as a cosubstrate in laboratory settings. However, it exhibits much lower affinity and transaminase activity towards phenylalanine.
Celluar localization	Cytosol;Mitochondrion;
UniPort	P17735