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Rabbit Anti-TAB1 Polyclonal Antibody#abs132746

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Description

Catalog-specification	Delivery time	USD price
abs132746-100ug	1-2 Weeks	301.0
abs132746-50ug	1-2 Weeks	201.0

Overview
catalog	abs132746
Description	An essential mediator in the communication pathway between TGFB receptors and MAP3K7/TAK1 is believed to be present in the form of a protein encoded by a specific gene. This molecule may hold considerable significance in the development of mammals during embryogenesis and beyond.
Other names	2310012M03Rik、3'-Tab1、MAP3K7IP 1、MAP3K7IP1、MGC57664、Mitogen activated protein kinase kinase kinase 7 interacting protein 1、Mitogen-activated protein kinase kinase kinase 7-interacting protein 1、TAB 1、TAB1、TAB1_HUMAN、TAK1 binding protein 1、TAK1-binding protein 1、TGF beta activated kinase 1 binding protein 1、TGF-beta activated kinase 1/MAP3K7 binding protein 1、TGF-beta-activated kinase 1 and MAP3K7-binding protein 1、TGF-beta-activated kinase 1-binding protein 1、Transforming growth factor beta activated kinase binding protein 1。 Let's rearrange the above information to generate a highly similar content: MAP3K7IP1, also known as TAB1 or TAK1-binding protein 1, is a key regulatory protein that interacts with mitogen-activated protein kinase kinase kinase 7 (MAP3K7) and plays a crucial role in various cellular processes. It is encoded by the gene 2310012M03Rik and also known as 3'-Tab1 or MGC57664. TAB1 is involved in the activation of TGF-beta-activated kinase 1 (TAK1) and binds to both TGF-beta-activated kinase 1 and MAP3K7. This binding protein is essential for signal transduction pathways mediated by TAK1 and MAP3K7, contributing to the regulation of cell growth, differentiation, and immune responses. The multifunctional nature of TAB1 highlights its importance in cellular signaling networks.
Source	Rabbit
Specificity	The detection of total TAB1 at its endogenous levels is enabled by the TAB1 antibody. It is important to rearrange the original content to present a similar meaning in a different manner.
Species Reactivity	Human;Mouse
Antigen	TAB1
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	55 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification. A highly refined product was achieved through this process.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.
Tissue specificity	Ubiquitous.
Posttranslational modification	Monoubiquitinated. Deubiquitinated by Y.enterocolitica YopP.
Celluar localization	Cytosol;Endosome;Nucleus;
UniPort	Q15750