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Rabbit Anti-SHB Polyclonal Antibody#abs134797

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Description

Catalog-specification	Delivery time	USD price
abs134797-100ug	1-2 Weeks	301.0
abs134797-50ug	1-2 Weeks	201.0

Overview
catalog	abs134797
Other names	bA3J10.2: A gene known as bA3J10.2 has been identified as having a relationship with other proteins and molecules within the human body. Research is being conducted to understand the precise role this gene plays in various cellular processes. OTTHUMP00000021397: Another intriguing molecular entity known as OTTHUMP00000021397 has caught the attention of scientists. Studies are underway to determine the specific functions and interactions of this molecule, which could provide valuable insights into biological pathways and disease development. RP11 3J10.8 and RP113J10.8: These two closely related genes, RP11 3J10.8 and RP113J10.8, are currently being investigated to elucidate their role in cellular signaling and molecular pathways. It is believed that these genes play a crucial part in regulating various biological processes, and further research is needed to fully comprehend their significance. SH2 domain containing adapter protein B: A fascinating protein named SH2 domain containing adapter protein B has recently garnered attention from researchers. This protein is known to be involved in mediating cellular communication and signal transduction. Scientists are studying its functions and interactions with other molecules to unravel its exact role in cellular processes. SHB (Src homology 2 domain containing) adaptor protein B: The SHB adaptor protein, also known as the Src homology 2 domain containing adaptor protein B, is a key player in cellular signaling. It acts as an intermediary in transmitting signals from various receptors to downstream signaling molecules. Ongoing research aims to determine the precise mechanisms by which this protein modulates cellular responses. SHB adaptor protein (a Src homology 2 protein): The SHB adaptor protein, a member of the Src homology 2 protein family, is currently being investigated for its role in cellular signaling and molecular networks. Scientists are exploring its functions and associations with other proteins to gain a deeper understanding of its involvement in cellular processes. Shb (SHB_HUMAN): The Shb protein, also known as SHB_HUMAN, is a fascinating molecule with potential implications in diverse biological pathways. Scientists are currently unraveling its role in cellular signaling and exploring its interactions with other molecules in order to shed light on its functional significance. Src homology 2 domain containing adaptor protein B: The Src homology 2 domain containing adaptor protein B is a captivating molecule that plays a crucial role in cellular communication and signal transduction pathways. Researchers are actively investigating its functions and associations with other molecules to decipher its precise role in cellular processes. Src homology 2 protein: The Src homology 2 protein, part of a family of signaling molecules, is an intriguing entity that modulates various cellular responses. Its functions and interactions with other proteins are currently under investigation to gain insight into its involvement in cellular signaling and molecular networks.
Source	Rabbit
Specificity	The total SHB levels can be assessed using the SHB Antibody, which specifically detects endogenous quantities of SHB protein in a sample.
Species Reactivity	Human;Mouse
Antigen	SHB
Application	The dilution ratios for Western Blot (WB) range from 1:500 to 1:1000, while for Immunofluorescence (IF) and Immunocytochemistry (ICC) they range from 1:100 to 1:500. For ELISA assays using peptides, the recommended dilution range is between 1:20000 and 1:40000. It is essential to follow these dilution guidelines to obtain accurate and reliable results in experimental protocols.
Immunogen	A synthesized peptide.
MW	55 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography was employed to purify the antiserum, with the SulfoLink™ Coupling Resin being utilized.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, it is recommended to keep the product stored at -20 °C for a duration of one year. It is important to avoid subjecting it to repeated freeze and thaw cycles in order to preserve its integrity.
Storage buffer	The Rabbit IgG comes in a phosphate buffered saline solution with a pH level of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store it at a temperature of -20 °C. The product is known to be stable for a period of 12 months from its date of receipt.
Target
Background	Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Tissue specificity	Widely expressed.
Posttranslational modification	Phosphorylated upon PDGFRA, PDGFRB, TCR, IL2 receptor, FGFR1 or VEGFR2 activation.
Celluar localization	Cytosol;Nucleus;Plasma Membrane;
UniPort	Q15464