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Rabbit Anti-RASA3 Polyclonal Antibody#abs134688

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Description

Catalog-specification	Delivery time	USD price
abs134688-100ug	1-2 Weeks	301.0
abs134688-50ug	1-2 Weeks	201.0

Overview
catalog	abs134688
Other names	GAP III, also known as GTPase activating protein III or RASA3, is a member of the GTPase activating protein 1 family. It is also referred to as GAP1(IP4BP), GAP1IP4BP, Inositol 1 3 4 5 tetrakisphosphate binding protein, or Ins P4-binding protein. Other aliases for RASA3 include Inositol 1345 tetrakisphosphate binding protein, Ins P4 binding protein, Ins(1 3 4 5)P4 binding protein, MGC46517, MGC47588, Ras GTPase activating protein 3, or Ras GTPase-activating protein 3. RASA3 plays a role in the activation of RAS p21 protein and is encoded by the RASA3 gene in humans.
Source	Rabbit
Specificity	The RASA3 Antibody is capable of identifying total RASA3 levels that are present naturally within an organism. To produce similar content, the text could be paraphrased as follows: The detection ability of the RASA3 Antibody extends to the identification of endogenous levels of total RASA3.
Species Reactivity	Human;Mouse;Rat
Antigen	RASA3
Application	The recommended dilutions for Western Blot (WB) are 1:500~1:1000, for Immunofluorescence (IF)/Immunocytochemistry (ICC) are 1:100-1:500, and for Enzyme-Linked Immunosorbent Assay (ELISA) using peptide are 1:20000-1:40000. It is important to follow these dilution guidelines to ensure accurate and reliable results in your experiments. Make sure to adjust your dilutions accordingly for optimal detection of your target protein.
Immunogen	A synthesized peptide.
MW	96 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography was employed to purify the antiserum using SulfoLink™ Coupling Resin. The process involved selecting a specific peptide sequence that the antiserum could bind to, and attaching it to the resin. This allowed the antiserum to selectively bind to the peptide sequence, and subsequently be separated from other components in the mixture. Overall, this method provided a highly effective means of obtaining a purified antiserum with high specificity and selectivity.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the substance, it is advisable to keep it in a freezer at -20 °C for a period of one year. It is crucial to avoid repeated freeze-thaw cycles to prevent any degradation of the substance. Take necessary measures to ensure that the substance remains in optimal condition during storage.
Storage buffer	The recommended storage conditions for Rabbit IgG are at a temperature of -20 °C. The IgG should be stored in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that the stability of the IgG is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q14644