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Rabbit Anti-RAD54B Polyclonal Antibody#abs138575

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Description

Catalog-specification	Delivery time	USD price
abs138575-100ug	1-2 Weeks	301.0
abs138575-50ug	1-2 Weeks	201.0

Overview
catalog	abs138575
Other names	One of the important proteins involved in repairing DNA and recombination is RAD54B. It belongs to the EC 3.6.1.- group of enzymes and is also known as Fibrinogen Silencer Binding Protein (FSBP) or RAD54 Homolog B. Its role in DNA repair and recombination is significant as it helps in maintaining the integrity of the genetic material in our cells. The FSBP function of RAD54B also plays an essential role in regulating the expression of genes involved in blood clotting. So, RAD54B is a multifunctional protein that has critical roles to play in various cellular processes.
Source	Rabbit
Specificity	The total RAD54B can be detected by the RAD54B Antibody, which is capable of identifying the endogenous levels. To create similar content, the information from the original text should be rearranged without changing the meaning.
Species Reactivity	Human
Antigen	RAD54B
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human RAD54B.
MW	102 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography, employing SulfoLink™ Coupling Resin, was utilized to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	One should avoid repeated freeze/thaw cycles and store the item for a year at -20 °C. It is important to note that the content should be highly similar to the original text.
Storage buffer	This product contains rabbit IgG in a phosphate buffered saline solution with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20°C, and can remain stable for up to 12 months from the date of receipt.
Target
Background	This protein is essential for DNA repair and the process of mitotic recombination. It works hand-in-hand with other RAD52 epistasis group members to actively participate in recombination processes. Its role is pivotal in maintaining genetic stability and preventing mutations. By functioning as part of a finely tuned network of proteins, this protein ensures that DNA damage is repaired quickly and efficiently. Its intricate molecular interactions make it a crucial component of the cellular machinery that preserves genomic integrity.
Tissue specificity	Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
Celluar localization	Nucleus;
UniPort	Q9Y620