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Rabbit Anti-Rab11-FIP4 Polyclonal Antibody#abs140529

Kindly note that the mentioned price is for your reference only. To obtain the actual price details, kindly get in touch with our seller Vecent. Appreciate your understanding. Western blot analysis Rab11-FIP4 using HepG2 whole cell lysates This product is for research use only, not for use in...

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Description

Catalog-specification	Delivery time	USD price
abs140529-100ug	1-2 Weeks	301.0
abs140529-50ug	1-2 Weeks	201.0

Kindly note that the mentioned price is for your reference only. To obtain the actual price details, kindly get in touch with our seller Vecent. Appreciate your understanding.

Overview
catalog	abs140529
Other names	RAB11 family interacting protein 4, also known as RAB11 FIP4 or Rab11 FIP4 like, is a protein with various biomedical and cellular functions. This protein is encoded by the genes RGD1305063 and RP23-271B20.4. It plays an important role in vesicle trafficking, secretion, and recycling. RAB11 FIP4 is involved in regulating endocytic trafficking of different types of receptors, including transferrin receptor, adiponectin receptor, and insulin receptor. Additionally, RAB11 FIP4 is involved in membrane trafficking and cellular polarization, making it an important protein for cellular development and differentiation. Overall, RAB11 FIP4 is an essential protein for normal cellular function and development.
Source	Rabbit
Specificity	The Rab11-FIP4 Antibody is specifically designed to detect overall expression of Rab11-FIP4 in the body. This antibody can identify endogenous levels of Rab11-FIP4, indicating the amount of this protein present in the body.
Species Reactivity	Human
Predictive reaction species	Pig;Rabbit;Bovine;Horse;Chicken
Antigen	Rab11-FIP4
Application	The dilution ratio for Western Blot is 1:1000, while for Immunofluorescence (IF) and Immunocytochemistry (ICC) it ranges from 1:100 to 1:500. For Enzyme-Linked Immunosorbent Assay (ELISA) using peptide, the dilution is between 1:20000 and 1:40000. We can rearrange the above information to create a similar content as follows: When performing Western Blot, the recommended dilution ratio is 1:1000. However, for Immunofluorescence and Immunocytochemistry techniques, it is advised to dilute the samples in the range of 1:100 to 1:500. In the case of ELISA using peptide, a dilution of 1:20000 to 1:40000 is often employed.
Immunogen	One possible way to rearrange the content while maintaining its meaning: The peptide synthesized was obtained from human Rab11-FIP4. It is designed to have a high degree of similarity with the original protein sequence. The goal is to study the function and interaction of Rab11-FIP4 with other cellular components, and potentially develop new drugs or therapies based on its properties. The peptide can be used in various experiments, such as binding assays, imaging, or biochemical assays. Its production requires specialized equipment and expertise, and quality control is essential to ensure its purity and stability. Overall, the synthesized peptide represents a valuable tool for investigating the complex mechanisms of intracellular trafficking and signaling, and may open up new avenues for medical research and treatment.
MW	72kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was accomplished through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum shelf life, it is recommended that the product be stored at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles as this can impact its quality and effectiveness. Proper storage and handling of the product will help to ensure its integrity and efficacy over time.
Storage buffer	The rabbit IgG is suspended in a solution of phosphate buffered saline, with a pH of 7.4, and 150mM of NaCl. Additionally, there is a small amount of sodium azide present, at a concentration of 0.02%. Finally, the solution also contains 50% glycerol, and should be stored at a temperature of -20 °C. This solution can last for up to 12 months, starting from the date of receipt, so long as it is properly stored and maintained.
Target
Background	Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6.
Tissue specificity	Present at high level in testis (at protein level). Weakly expressed in other tissues.
Celluar localization	Cytoskeleton;Endosome;Extracellular region or secreted;
UniPort	Q86YS3