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Rabbit Anti-PSMD3 Polyclonal Antibody#abs140724

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Description

Catalog-specification	Delivery time	USD price
abs140724-50ug	1-2 Weeks	201.0
abs140724-100ug	1-2 Weeks	301.0

Overview
catalog	abs140724
Other names	Tissue specific transplantation antigen 2, also known as proteasome subunit p58 or 26S proteasome regulatory subunit S3, is a non-ATPase regulatory subunit of the 26S proteasome. It is encoded by the PSMD3 gene in humans. The protein plays a crucial role in the degradation of targeted proteins within the proteasome. Its function is essential for maintaining cellular homeostasis and regulating various cellular processes. PSMD3, or RPN3, is commonly referred to as the 26S proteasome non-ATPase regulatory subunit 3. It is also known by the alternative name Proteasome (prosome, macropain) 26S subunit non ATPase 3. OTTHUMP00000164347 is another identifier associated with this protein.
Source	Rabbit
Specificity	The PSMD3 Antibody is designed to recognize total PSMD3 levels present in the body. It specifically targets the endogenous PSMD3 protein. The detection capability of this antibody enables researchers to investigate the overall expression of PSMD3 in various biological samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Xenopus;Dog;Horse;Sheep;Bovine
Antigen	PSMD3
Application	Based on the original text information, the suggested dilution range for WB is 1:500~1:1000. For IHC, the recommended dilution range is 1:50~1:200. As for IF/ICC, the suitable dilution range is 1:100-1:500. In the case of ELISA using peptides, the optimal dilution range is 1:20000-1:40000.
Immunogen	A synthesized peptide.
MW	61 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum. Please generate a highly similar content by rephrasing the original information while maintaining its context.
Clonality	Polyclonal Antibody
Stability & Storage	One year of storage at -20 °C is recommended. To maintain the quality of the product, it is crucial to avoid subjecting it to repeated freeze-thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
Celluar localization	Cytosol;Extracellular region or secreted;Nucleus;
UniPort	O43242