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Rabbit Anti-prouty4 Polyclonal Antibody#abs136995

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Description

Catalog-specification	Delivery time	USD price
abs136995-100ug	1-2 Weeks	301.0
abs136995-50ug	1-2 Weeks	201.0

Overview
catalog	abs136995
Other names	Sprouty homolog 4, also known as protein sprouty homolog 4 or SPRY 4, is a gene that is homologous to the sprouty gene found in Drosophila. It is denoted by various names such as Spry-4, Spry4, and SPY4_HUMAN. This gene plays a crucial role in biological processes and is highly conserved across different species. Its functions and mechanisms contribute to the regulation of cell growth, development, and signaling pathways. Understanding the intricate workings of Sprouty homolog 4 can provide insights into various physiological and pathological processes in organisms.
Source	Rabbit
Specificity	The prouty 4 Antibody can recognize the amount of total prouty 4 that is naturally present in an organism. This information can be used to study the function and localization of prouty 4 in various biological processes. It is important to note that the antibody only detects the endogenous levels of prouty 4, meaning that artificially introduced prouty 4 may not be recognized.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	prouty4
Application	The recommended dilution for Western blot (WB) ranges from 1:1000 to 1:3000, while for immunohistochemistry (IHC) it is 1:200. For ELISA assays using a peptide, the suggested dilution is between 1:20000 and 1:40000. Please note that the above information has been rearranged to provide a similar content based on the original text.
Immunogen	A synthesized peptide derived from human prouty 4.
MW	33 kDa.
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the product's quality, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is crucial to avoid exposing the product to repetitive freeze and thaw cycles which can potentially harm its integrity.
Storage buffer	This product contains rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For maximum stability, the product should be stored at a temperature of -20°C. It is advisable to use the product within 12 months from the date of receipt to ensure optimal performance.
Target
Background	Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Celluar localization	Plasma Membrane;
UniPort	Q9C004