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Rabbit Anti-glut2 Polyclonal Antibody#abs136996

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Description

Catalog-specification	Delivery time	USD price
abs136996-100ug	1-2 Weeks	301.0
abs136996-50ug	1-2 Weeks	201.0

Overview
catalog	abs136996
Other names	The liver is responsible for a lot of functions in the body, including regulating glucose levels. One of the key players in this process is the Glucose Transporter 2, also known as GLUT2 or GTT2. This protein is a type of facilitated glucose transporter that is prominently expressed in the liver. The GLUT2 protein is encoded by the Solute Carrier Family 2 Facilitated Glucose Transporter Member 2 gene, which is also referred to as SLC2A2. This gene is responsible for producing the protein that allows glucose to enter liver cells. Interestingly, the Glucose Transporter 2 is not only found in the liver, but also in pancreatic beta cells, where it regulates insulin secretion. This makes it a crucial component of glucose homeostasis in the body, helping to maintain stable blood sugar levels. Overall, the Glucose Transporter 2 is a vital protein that plays a crucial role in liver function and glucose regulation. Its importance has made it a subject of intense study in the medical and scientific communities, as researchers seek to understand more about its mechanisms and potential therapeutic applications.
Source	Rabbit
Specificity	The glut2 Antibody has the ability to identify total glut2 levels that are naturally present in the body. A similar piece of information can be created by arranging the original text in a different manner.
Species Reactivity	Human;Mouse;Rat
Antigen	glut2
Application	The recommended dilution for Western blot is between 1:1000 and 1:3000, while for immunohistochemistry it is 1:200. When using ELISA with peptide, it is advisable to dilute the sample between 1:20000 and 1:40000. By following these dilutions, you can ensure optimal results in your experiments. It is important to note that these dilutions may vary based on the specific assay and the sample being tested. Always refer to the manufacturer's instructions for best practices and recommended dilutions.
Immunogen	A synthesized peptide derived from human glut2.
MW	57 kDa.
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum. Let me generate a highly similar content by rearranging the provided information: The purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the preservation of the product, it is recommended to store it at a temperature of -20°C for a duration of one year. To maintain its quality, it is crucial to prevent it from undergoing repeated freeze/thaw cycles.
Storage buffer	The recommended storage condition for Rabbit IgG is at -20°C. It is supplied in phosphate buffered saline with a pH of 7.4 and contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This product is stable for a period of 12 months from the date of receipt.
Target
Background	Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na+/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
Tissue specificity	Liver, insulin-producing beta cell, small intestine and kidney.
Posttranslational modification	N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
Celluar localization	Plasma Membrane;
UniPort	P11168