Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-OPRD1 Polyclonal Antibody#abs135345

Please note that the price provided is only for reference. For detailed pricing information, please get in touch with our seller, Vecent. It is important to emphasize that the content generated should be based on the original text information but presented in a highly similar manner. Instead of...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs135345-100ug	1-2 Weeks	301.0
abs135345-50ug	1-2 Weeks	201.0

Overview
catalog	abs135345
Other names	The Delta type opioid receptor, also known as DOR 1 or DOR1, is a vital protein found in humans and animals. It is part of the opioid receptor family and plays a crucial role in pain relief and mood regulation. The mDOR and Nbor are other names for this receptor, which is also known as the Delta-type opioid receptor. The DOR-1 is essential for the function of the body's natural pain-relieving system and is also responsible for the effects of opioid medication in the body. The Opioid receptor delta 1 or OPRD 1 is the official gene name for this receptor, while OPRD is the shorthand for this life-sustaining protein in humans. Understanding the role of the DOR1 receptor is essential for developing new treatments for pain management, drug addiction, and mental health disorders. It is a promising area of research that could lead to better therapies for a range of illnesses that affect millions of people worldwide.
Source	Rabbit
Specificity	The OPRD1 Antibody is capable of detecting the total levels of endogenous OPRD1 in the body. The content can be rearranged to create a similar statement that highlights the same information with different wording.
Species Reactivity	Human
Predictive reaction species	Rabbit;Bovine;
Antigen	OPRD1
Application	The dilution ratios for WB range from 1:500 to 1:1000, for IF it ranges from 1:100 to 1:500, and for ELISA (peptide) it ranges from 1:20000 to 1:40000. Additionally, the dilution range for the second ELISA (peptide) assay is also 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	36 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. Recombinant peptides attached to the resin were used to capture the target protein and isolate it from other unwanted proteins and contaminants. This method is highly effective in producing a pure and concentrated final product.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of your product, it is recommended to store it in a temperature-controlled environment set at -20 °C for a period of one year. It is important to avoid repeated cycles of freezing and thawing as this can lead to degradation of the product. By following these storage guidelines, you can ensure the product remains effective and stable for its intended use.
Storage buffer	The storage solution for rabbit IgG consists of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. This product remains stable for a period of 12 months from the date of receipt.
Target
Background	G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
Tissue specificity	Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
Posttranslational modification	N-glycosylated.Ubiquitinated. A basal ubiquitination seems not to be related to degradation. Ubiquitination is increased upon formation of OPRM1:OPRD1 oligomers leading to proteasomal degradation; the ubiquitination is diminished by RTP4.
Celluar localization	Plasma Membrane;
UniPort	P41143