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Rabbit Anti-Nuclear Factor1 Polyclonal Antibody#abs133552

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Description

Catalog-specification	Delivery time	USD price
abs133552-100ug	1-2 Weeks	301.0
abs133552-50ug	1-2 Weeks	201.0

Overview
catalog	abs133552
Other names	There are several genes that are associated with the CCAAT box binding transcription factor, including 1110047K16Rik, 9430022M17Rik, and CTF. Additionally, this transcription factor is also known as Nuclear factor I/A, NF-I/B, and NF-I/C, with multiple variations exist for each type. The function of this transcription factor is primarily involved in regulating gene expression and controlling various cellular processes such as proliferation, differentiation, and development. Interestingly, some of the genes that are associated with this transcription factor, such as Nfib and NFIX, have been linked to several developmental disorders and diseases. For instance, mutations in Nfib have been found to cause craniofrontonasal syndrome, while mutations in NFIX have been associated with Sotos syndrome. Therefore, further research is needed to better understand the role of the CCAAT box binding transcription factor and its associated genes in human health and disease.
Source	Rabbit
Specificity	The Nuclear Factor 1 Antibody is designed to detect total levels of Nuclear Factor 1 present in the body. This antibody is highly specific to endogenous Nuclear Factor 1 and is able to detect its presence accurately. By using this antibody, researchers are able to study the role of Nuclear Factor 1 in various physiological and pathological processes. Its reliable performance makes it a popular choice among scientists for their research studies.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Pig;Dog
Antigen	Nuclear Factor1
Application	The dilution range for Western blot (WB) is commonly performed at 1:500 to 1:1000, while for immunofluorescence (IF) or immunocytochemistry (ICC) it is usually done at a dilution of 1:100 to 1:500. For enzyme-linked immunosorbent assay (ELISA) using peptide antigens, the recommended dilution ranges from 1:20000 to 1:40000. These dilutions are crucial for achieving optimal results in these different experimental techniques.
Immunogen	A synthesized peptide.
MW	55 KD
Properties
Concentration	1mg/ml
purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Celluar localization	Nucleus;
UniPort	Q12857/O00712/P08651/Q14938