Rabbit Anti-NRIP1 Polyclonal Antibody#abs133019
Hi there, please note that the price mentioned above is only for reference. If you need more information on the actual price, we kindly request you to contact our seller Vecent. Thank you! Western blot analysis of NRIP1 expression in A498 (Human Kidney Carcinoma) Whole Cell Lysate ;,The lane on...
Description
| Catalog-specification | Delivery time | USD price |
abs133019-100ug | 1-2 Weeks | 301.0 |
abs133019-50ug | 1-2 Weeks | 201.0 |
Hi there, please note that the price mentioned above is only for reference. If you need more information on the actual price, we kindly request you to contact our seller Vecent. Thank you!
| Overview | |
catalog | abs133019 |
Description | Steroid receptors like NR3C1, NR3C2, and ESR1 are regulated by this protein, which modulates their transcriptional activation. Additionally, it plays a role in regulating transcriptional repression mediated by nuclear hormone receptors. The protein's function is to fine-tune the gene expression patterns influenced by these receptors. |
| Other names | NRIP1, also known as nuclear receptor-interacting protein 1 or receptor-interacting protein 140, is a human protein. It is commonly referred to as RIP 140 or RIP140. NRIP1 is a nuclear factor that interacts with various nuclear receptors, playing a crucial role in modulating gene expression. This protein's versatile functions make it a significant player in various biological processes. By rearranging the information provided, a modified description of NRIP1 can be created: Nuclear factor RIP140, also called NRIP1 or receptor-interacting protein 140, is a vital human protein. It interacts with nuclear receptors and plays a significant role in regulating gene expression. NRIP1's versatility enables it to be involved in diverse biological processes, making it an essential cellular component. RIP140, NRIP1, and nuclear receptor interacting protein 1 are interchangeable names for this protein. |
| Source | Rabbit |
| Specificity | The NRIP1 antibody can identify the total amount of NRIP1 present in the body, including the endogenous levels. You can create similar content by altering the wording while staying true to the original information. |
| Species Reactivity | Human;Mouse |
| Predictive reaction species | Xenopus;Rabbit;Pig;Sheep;Horse;Bovine;Chicken |
| Antigen | NRIP1 |
| Application | The dilution ranges for Western Blot (WB) are 1:500 to 1:2000, for Immunohistochemistry (IHC) are 1:50 to 1:200, and for ELISA (peptide) are 1:20000 to 1:40000. Can you please generate a similar content by reordering the information provided above, while ensuring that the generated content is derived from the original text information? |
| Immunogen | A synthesized peptide. |
| MW | 150 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. Our method resulted in a highly purified antiserum that is ideal for use in various applications. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To ensure optimal storage conditions, it is recommended to keep the product at a temperature of -20 °C for up to a year. It is important to avoid subjecting the product to repeated freeze/thaw cycles, as this can affect its stability and performance. By adhering to these storage guidelines, you can help ensure that the product remains effective and usable for longer periods of time. |
| Storage buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Target | |
Background | Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. |
| Tissue specificity | Expressed in a circadian manner in the liver (at protein level). |
| Posttranslational modification | Acetylation regulates its nuclear translocation and corepressive activity (By similarity). Acetylation abolishes interaction with CTBP1. Phosphorylation enhances interaction with YWHAH. |
| Celluar localization | Nucleus; |
| UniPort | P48552 |
Western blot analysis of NRIP1 expression in A498 (Human Kidney Carcinoma) Whole Cell Lysate ;,The lane on the left is treated with the antigen-specific peptide.
This product is for research use only, not for use in diagnostic prodecures or in human.
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