Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-NMUR2 Polyclonal Antibody#abs133200

Please note that the stated price is for your reference only. If you require more detailed pricing information, please do not hesitate to contact our sales representative, Vecent. We highly recommend that you get in touch with Vecent to discuss your needs and budget. Thank you for considering...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs133200-100ug	1-2 Weeks	301.0
abs133200-50ug	1-2 Weeks	201.0

Overview
catalog	abs133200
Description	The neuropeptides neuromedin-U and neuromedin-S bind to a specific receptor in the body. This receptor is responsible for mediating the effects of these neuropeptides. Without this receptor, the body would not be able to respond to or process these important signaling molecules. Understanding the role of this receptor in neuromedin-U and neuromedin-S signaling is critical for developing new therapies for a variety of neurological and psychiatric disorders. Through continued research, scientists hope to elucidate the precise mechanisms of this receptor and its interactions with these neuropeptides.
Other names	The G protein coupled receptor FM4, also known as TGR 1, is a member of the growth hormone secretagogue receptor family. It is also referred to as G-protein coupled receptor FM-4 or TGR-1. The receptor is involved in signaling pathways that regulate various physiological processes, such as motor control, behavior, and the release of hormones. Another important function of FM4 is in the regulation of appetite, and is activated by neuromedin U receptor 2 (NMU R2) or NMU2R. The receptor is expressed in various tissues including the brain, pancreas, and gastrointestinal tract. Understanding the function and regulation of FM4 may provide new insights into the development of therapies for metabolic disorders and obesity.
Source	Rabbit
Specificity	The endogenous levels of total NMUR2 can be accurately detected using the NMUR2 antibody.
Species Reactivity	Human
Antigen	NMUR2
Application	The dilution ratios for the Western blot are 1:500 to 1:2000, while the dilution ratios for the immunohistochemistry are 1:50 to 1:200. For ELISA with peptide, the dilution ratios range from 1:20000 to 1:40000.
Immunogen	A synthesized peptide.
MW	46 kDa
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin in peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store at -20 °C for a duration of one year and prevent freezing and thawing cycles from occurring repeatedly.
Storage buffer	The content is generated using language models in a different manner from ChapGPT. The following content has been rearranged based on the original text information: In a solution of phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol, there is Rabbit IgG.
Target
Background	Receptor for the neuromedin-U and neuromedin-S neuropeptides.
Tissue specificity	Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus.
Celluar localization	Plasma Membrane;
UniPort	Q9GZQ4