Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-NKIRAS1 Polyclonal Antibody#abs138587

Please note that the mentioned price is only for your reference. For the detailed price, we kindly request you to get in touch with our seller, Vecent. We advise generating content in a different manner, not according to the way ChapGPT generates content, but by using a language model to deliver...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs138587-100ug	1-2 Weeks	301.0
abs138587-50ug	1-2 Weeks	201.0

Overview
catalog	abs138587
Other names	I suggest including the rearranged content based on the original text information. Here it is: The gene 2400004O09Rik encodes a protein called I-kappa-B-interacting Ras-like protein 1, also known as Kappa B Ras protein 1 or KBRAS1. This protein interacts with the NF-kappa-B inhibitor, playing a role in inhibiting the NF-kappa-B signaling pathway. NKIRAS 1, another name for this protein, is crucial for regulating cell processes and immune responses. KappaB-Ras1 functions as a modulator of NF-kappa-B activity, participating in various cellular functions. Overall, KBRAS1 is associated with the regulation of key signaling pathways and contributes to the intricate network of cellular processes.
Source	Rabbit
Specificity	The total NKIRAS1 levels within the body can be detected by using the NKIRAS1 Antibody, which is capable of identifying endogenous amounts. To create a similar piece of content, the text could be rephrased as follows: By utilizing the NKIRAS1 Antibody, it is possible to detect overall levels of NKIRAS1 that exist naturally in the body. This antibody is capable of recognizing these endogenous amounts.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Dog;Horse
Antigen	NKIRAS1
Application	The recommended dilution factors for WB range from 1:1000 to 1:3000, for IHC it's 1:200, and for ELISA (peptide) it's 1:20000 to 1:40000. These ratios ensure optimal results when using the respective methods. It's crucial to carefully adjust the dilution factors based on the experimental conditions and the quality of the samples being studied. By doing this, accurate and reproducible results can be achieved, leading to insightful findings and discoveries.
Immunogen	A synthesized peptide derived from human NKIRAS1.
MW	22 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was achieved through peptide affinity chromatography. The process selectively isolates the desired peptide, resulting in a highly purified product.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to note that you should avoid subjecting the product to repeated freeze/thaw cycles as this can compromise its stability and effectiveness. Therefore, it is advisable to handle the product with care to ensure its desired efficacy.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Tissue specificity	Widely expressed.
UniPort	Q9NYS0