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Rabbit Anti-NFYC Polyclonal Antibody#abs134561

Rabbit Anti-NFYC Polyclonal Antibody#abs134561

Please note that the price mentioned above is only for reference purposes. For more details, kindly get in touch with our seller Vecent. It is essential to know that the generated content will not be similar to the original text as it will be based on language models and not on ChapGPT generated...

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Description

Catalog-specificationDelivery timeUSD price

abs134561-100ug

1-2 Weeks

301.0

abs134561-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is only for reference purposes. For more details, kindly get in touch with our seller Vecent. It is essential to know that the generated content will not be similar to the original text as it will be based on language models and not on ChapGPT generated content.


Overview

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abs134561
Other namesCAAT box DNA binding protein subunit C, also known as CCAAT transcription binding factor subunit gamma, is a crucial factor in regulating gene expression. This protein belongs to the NF-Y family of transcription factors and is responsible for binding to the CAAT box promoter element of target genes. As a subunit of the CCAAT binding factor, CBFC plays an essential role in modulating gene expression in eukaryotic cells. HSM, or histone H1 transcription factor large subunit 2A, is another name for NF-YC and is involved in various biological processes in cells, including cell cycle control, proliferation, and differentiation.
As a transcription factor, CBFC is critical for regulating the transcription of a variety of genes, which is essential for various cellular processes. The NF-YC protein, along with the other subunits of the CCAAT binding factor, forms a complex that plays a crucial role in the binding and regulation of gene expression. Hence, NF-YC is an essential factor in providing specificity to transcriptional regulation.
This protein is encoded by the NFYC gene, which is located on chromosome 1 in humans. The gene consists of six exons and spans approximately 27 kb of genomic DNA. NFYC is known to have multiple splice isoforms, with the exact number of isoforms not yet fully characterized.
Overall, CAAT box DNA binding protein subunit C plays a critical role in regulating gene expression and is involved in various cellular processes. Due to its importance, this protein is an attractive target for developing therapeutics for various diseases, including cancer.
SourceRabbit
SpecificityThe total NFYC levels present in the body can be effectively detected using the NFYC Antibody, which specifically targets endogenous NFYC.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesZebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
AntigenNFYC
ApplicationFor Western blotting, dilute the antibody at a ratio of 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, use a dilution of 1:100 to 1:500. For ELISA using peptide as antigen, dilute the antibody at a ratio of 1:20000 to 1:40000. These are the recommended dilutions for optimal results.
ImmunogenA synthesized peptide.
MW50 KD
Properties

Concentration

1mg/ml

purificationPeptide affinity chromatography with SulfoLink™ Coupling Resin was utilized to purify the antiserum. Let's create alternative sentences to convey the same information:
- The antiserum underwent purification via peptide affinity chromatography, employing SulfoLink™ Coupling Resin.
- Utilizing SulfoLink™ Coupling Resin, peptide affinity chromatography was employed to purify the antiserum.
- Purification of the antiserum was achieved using SulfoLink™ Coupling Resin in peptide affinity chromatography.
- Peptide affinity chromatography, utilizing SulfoLink™ Coupling Resin, was employed to purify the antiserum.
ClonalityPolyclonal Antibody
Stability & StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

Celluar localizationNucleus;
UniPortQ13952


This product is for research use only, not for use in diagnostic prodecures or in human.


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