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Rabbit Anti-NETO2 Polyclonal Antibody#abs137672

Please note that the price mentioned is only for reference purposes. For detailed pricing information, kindly get in touch with our sales representative, Vecent. Also, the content generated should be very different from how ChapGPT generates content to avoid mimicking the same pattern. Western...

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Description

Catalog-specification	Delivery time	USD price
abs137672-100ug	1-2 Weeks	301.0
abs137672-50ug	1-2 Weeks	201.0

Overview
catalog	abs137672
Other names	Brain specific transmembrane protein 2 (NETO2), also known as Neuropilin and tolloid-like protein 2, is a transmembrane protein that plays a role in synaptic function. It contains two CUB and one LDL receptor class A domains, which are important for protein-protein interactions. NETO2 is primarily expressed in the brain and is involved in the regulation of ionotropic glutamate receptors. It has been suggested that NETO2 may play a role in the development and plasticity of synapses. Variations in the NETO2 gene have been associated with neurological disorders such as autism and epilepsy. Overall, NETO2 is an important protein for brain function and may serve as a potential target for therapeutic intervention in neurological diseases.
Source	Rabbit
Specificity	The ability of NETO2 Antibody to recognize total endogenous NETO2 levels is known. To produce a similar content based on the original text information, the following rearrangement can be done: "Detection of endogenous total NETO2 is achieved using NETO2 Antibody."
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Rabbit;Sheep;Dog;
Antigen	NETO2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human NETO2.
MW	60 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. The resulting product is highly similar to the original substance and has been refined to ensure its quality and effectiveness.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, keep at a temperature of -20 °C for a period of one year. It is essential to avoid exposing the specimen to repeated cycles of freezing and thawing.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity).
Posttranslational modification	N-glycosylated.
UniPort	Q8NC67