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Rabbit Anti-NCR3 Polyclonal Antibody#abs134523

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Description

Catalog-specification	Delivery time	USD price
abs134523-100ug	1-2 Weeks	301.0
abs134523-50ug	1-2 Weeks	201.0

Overview
catalog	abs134523
Other names	The Natural Killer (NK) cell receptor p30, also known as CD337 or LY117, is a crucial component in the activation of NK cells. It triggers the activation of the NK A1 receptor and plays a vital role in the immune response. The CD337 antigen, also referred to as Lymphocyte antigen 117, is another name for this receptor. It is also known as MALS, which stands for Natural cytotoxicity triggering receptor 3. Additionally, it goes by the names Natural killer cell p30 related protein, Natural killer cell p30-related protein, Ncr3, NCTR3_HUMAN, and NK-p30, all of which represent different aspects of its function and characteristics. The manipulation of these names and rearrangement of the provided content generate a highly similar content that maintains the original text information.
Source	Rabbit
Specificity	The NCR3 Antibody is capable of identifying the total NCR3 present in the body at its natural levels. The antibody is specifically designed to detect endogenous quantities of NCR3. By utilizing this antibody, researchers can accurately analyze and study the overall expression and distribution of NCR3 in various biological samples. This facilitates a deeper understanding of the function and role of NCR3 in physiological processes and disease mechanisms.
Species Reactivity	Human;Rat
Antigen	NCR3
Application	For Western blotting, we recommend a dilution range of 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, a dilution range of 1:100 to 1:500 is optimal. When performing ELISA assays with peptides, we recommend a dilution range of 1:20000 to 1:40000. These dilution recommendations will help ensure accurate and reliable results for your experiments.
Immunogen	A synthesized peptide.
MW	30 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. Please generate similar content by rearranging the given information, while ensuring that the generated content is based on the original text. Do not engage in dialogue as in the ChapGPT conversation model, instead provide a completely different way of presenting text using the language model.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store it for a year at a temperature of -20 °C. Make sure to prevent any freeze/thaw cycles from occurring.
Storage buffer	This product contains Rabbit IgG which is suspended in a phosphate buffered saline solution with a pH level of 7.4. The solution also contains 150mM NaCl, 0.02% of sodium azide, and 50% glycerol. It is recommended to store the product at a temperature of -20 °C. The stability of the product is ensured for a period of 12 months from the date of purchase.
Target
Background	Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Tissue specificity	Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Celluar localization	Plasma Membrane;
UniPort	O14931