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Rabbit Anti-NCOA7 Polyclonal Antibody#abs134558

Please note that the price provided in this message is only for your reference. For the detailed and accurate pricing, please do not hesitate to contact our seller Vecent. Western blot analysis of extracts from LOVO cells, 3T3 cells and RAW264.7 cells, using NCOA7 antibody. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs134558-100ug	1-2 Weeks	301.0
abs134558-50ug	1-2 Weeks	201.0

Please note that the price provided in this message is only for your reference. For the detailed and accurate pricing, please do not hesitate to contact our seller Vecent.

Overview
catalog	abs134558
Other names	Estrogen receptor associated protein, also known as ERAP140, is a 140 kDa protein that is involved in the regulation of estrogen signaling. It is encoded by the gene 9030406N13Rik, also known as dJ187J11.3 or ESNA1. ERAP140 acts as a coactivator for estrogen nuclear receptors, such as Nbla00052 and Nbla10993. It is also known as nuclear receptor coactivator 7 and has alternative names like FLJ45605 and MGC88425. This protein plays a crucial role in mediating the effects of estrogen on gene transcription and cellular responses.
Source	Rabbit
Specificity	The NCOA7 Antibody has the ability to recognize and identify the total levels of endogenous NCOA7 in a given sample. This means that it can accurately detect all forms of NCOA7 protein present in the sample, without any bias or preference for any particular variant. With its high specificity and sensitivity, this antibody is an ideal tool for studying the expression and function of NCOA7 in various biological contexts. By using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying NCOA7-mediated biological processes, and potentially identify novel therapeutic targets for a range of diseases.
Species Reactivity	Human
Predictive reaction species	Rabbit
Antigen	NCOA7
Application	The dilutions for Western blotting range from 1:500 to 1:1000, while the dilutions for immunofluorescence/immunocytochemistry are between 1:100 and 1:500. For ELISA assays using a peptide substrate, the recommended dilutions are typically between 1:20000 and 1:40000.
Immunogen	A synthesized peptide.
MW	106 KD
Properties
Concentration	1mg/ml
purification	To purify the antiserum, SulfoLink™ Coupling Resin was used in peptide affinity chromatography. The chromatography process aimed to isolate specific peptides from the antiserum through the use of resin-bound ligands. With this process, a highly pure antiserum was achieved, ready for further use in various applications.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, it is recommended to store at a temperature of -20 °C for a year. Please be cautious about preventing the product from undergoing multiple freeze/thaw cycles.
Storage buffer	This product contains Rabbit IgG in a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The recommended storage temperature is -20 °C, and the product is expected to remain stable for up to 12 months from the date of receipt. It is important to follow these storage guidelines to ensure the optimal performance of this product in your experiments.
Target
Background	Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.
Tissue specificity	Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.
Celluar localization	Nucleus;
UniPort	Q8NI08