Rabbit Anti-NCAN Polyclonal Antibody#abs134538
Please note that the price given above is for reference only. For detailed pricing information, we kindly request you to reach out to our seller, Vecent. We assure you that our team will provide you with all the necessary details to make an informed decision. Thank you for your understanding....
Description
| Catalog-specification | Delivery time | USD price |
abs134538-100ug | 1-2 Weeks | 301.0 |
abs134538-50ug | 1-2 Weeks | 201.0 |
Please note that the price given above is for reference only. For detailed pricing information, we kindly request you to reach out to our seller, Vecent. We assure you that our team will provide you with all the necessary details to make an informed decision. Thank you for your understanding.
| Overview | |
catalog | abs134538 |
| Other names | Neurocan proteoglycan, also known as chondroitin sulfate proteoglycan 3 (Cspg3) or Ncan, is a crucial protein in the field of neuroscience. Its core protein, termed Neurocan, plays a significant role in various neurological processes. With its presence in the nervous system, it actively participates in neurodevelopment and synaptic plasticity. Neurocan proteoglycan serves as an essential molecular scaffold for axonal growth and guidance during neural circuit formation. Additionally, it contributes to the maintenance of neuronal morphology and regulates cell adhesion and migration. Through its intricate involvement in these functions, Ncan plays a pivotal role in shaping the intricate network of the nervous system. |
| Source | Rabbit |
| Specificity | The endogenous levels of total NCAN can be detected using the NCAN Antibody. |
| Species Reactivity | Human;Rat |
| Antigen | NCAN |
| Application | The dilution ranges for Western Blot (WB) are from 1:500 to 1:1000, for Immunofluorescence/Immunocytochemistry (IF/ICC) it is 1:100 to 1:500, and for ELISA (peptide) it is 1:20000 to 1:40000. These dilution ranges provide guidelines for the optimal concentration of antibodies or peptides to be used in these experiments. By adjusting the dilution ratios within these ranges, researchers can ensure accurate detection and quantification of their target molecules. It is essential to carefully optimize the dilution ratios to achieve reliable and reproducible results in WB, IF/ICC, and ELISA assays. |
| Immunogen | A synthesized peptide. |
| MW | 143 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | We utilized SulfoLink™ Coupling Resin in the peptide affinity chromatography process to purify the antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain the integrity of the product, it is advisable to store it at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing. This will ensure that the product remains stable and effective over the given period. |
| Storage buffer | -20°CIgG，pH 7.4，150mM NaCl，0.02%50%。12。，。 |
Target | |
Background | By binding to neural cell adhesion molecules (NG-CAM and N-CAM), it is believed that Chondroitin sulfate proteoglycan may play a role in modulating neuronal adhesion and neurite growth during development. In addition, this proteoglycan has the ability to bind to hyaluronic acid. These properties suggest that Chondroitin sulfate proteoglycan could have implications for neural plasticity and may be involved in shaping the structure and function of the developing brain. |
| Tissue specificity | Brain. |
| Posttranslational modification | O-glycosylated. |
| Celluar localization | Extracellular region or secreted;Golgi apparatus;Lysosome; |
| UniPort | O14594 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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