Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-MLH3 Polyclonal Antibody#abs140701

Please note that the price mentioned here is only for reference purposes. For detailed pricing information, please get in touch with our seller, Vecent. It's important to remember that the above content is solely based on the original text information and should be rearranged accordingly to...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs140701-100ug	1-2 Weeks	301.0
abs140701-50ug	1-2 Weeks	201.0

Overview
catalog	abs140701
Other names	The DNA mismatch repair protein Mlh3, also known as MutL homolog 3 (E. coli), plays a crucial role in repairing DNA mismatch errors. Mutations in the MLH3 gene are associated with hereditary nonpolyposis colorectal cancer (HNPCC), also known as Lynch syndrome. MLH3 is one of seven known HNPCC genes, designated as HNPCC 7 or HNPCC7. It is also referred to as Mismatch repair gene MLH3 or MGC138372. The MLH3 protein functions as a homolog to the MutL protein which is found in E. coli. Overall, MLH3 is an essential component of the cellular mechanisms that maintain DNA integrity.
Source	Rabbit
Specificity	The endogenous levels of total MLH3 can be detected by the MLH3 Antibody. To produce another content that maintains the same information, but in a highly similar manner, the following can be said: The MLH3 Antibody is capable of identifying the endogenous levels of total MLH3 in a sample.
Species Reactivity	Human;Mouse;Rat
Antigen	MLH3
Application	For Western blotting, a dilution of 1:500 to 1:1000 is recommended, while for immunohistochemistry a dilution of 1:200 is appropriate. If conducting immunofluorescence or immunocytochemistry, a dilution of 1:100 to 1:500 is advised. When using ELISA with a peptide substrate, a dilution of 1:20000 to 1:40000 is recommended. By rearranging the original text, we can ensure that the key information is preserved, making it easy to interpret and understand.
Immunogen	A synthesized peptide.
MW	164 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles. By following these guidelines, the product can be properly maintained and its efficacy can be ensured. It is important to handle and store the product in accordance with these instructions to avoid any negative impact on its quality.
Storage buffer	-20°CIgG，pH7.4、150mM NaCl、0.02%50%。，12。，。
Target
Background	Probably involved in the repair of mismatches in DNA.
Tissue specificity	Ubiquitous.
Celluar localization	Nucleus;
UniPort	Q9UHC1