Rabbit Anti-MINPP1 Polyclonal Antibody#abs141268

Rabbit Anti-MINPP1 Polyclonal Antibody#abs141268

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Description

Catalog-specificationDelivery timeUSD price

abs141268-100ug

1-2 Weeks

301.0

abs141268-50ug

1-2 Weeks

201.0

Please note that the price mentioned above is only for your reference. for the actual price, kindly contact our esteemed seller Vecent. It is important to ensure that the information provided aligns with the original text. Therefore, kindly refrain from using the ChapGPT generated content while communicating and instead opt for language model-generated content to maintain clarity.


Overview

catalog

abs141268
Other namesThere are several different names for the enzyme that catalyzes the hydrolysis of inositol phosphates, which are important signaling molecules in cells. Some of these names include inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase, 5)-P(4) 3-phosphatase, and multiple inositol polyphosphate phosphatase 1. Additionally, the enzyme has been given several different abbreviations, such as MINPP2 and MIPP. It is clear that this enzyme plays an important role in regulating cellular signaling pathways, and researchers are working to better understand its function and potential therapeutic applications.
SourceRabbit
SpecificityThe MINPP1 Antibody is capable of detecting total levels of endogenous MINPP1. This information can be restated by saying that the antibody is effective at detecting the complete amount of MINPP1 present naturally within the body.
Species ReactivityHuman;Mouse;Rat
Predictive reaction speciesHorse;Rabbit;
AntigenMINPP1
ApplicationWB(Western blot),1:5001:1000。(IF)(ICC),1:1001:500。(ELISA),1:200001:40000。
,。
ImmunogenA synthesized peptide.
MW60 KD
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, the purification of the antiserum was performed via peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo preserve the quality of this product, it is recommended to store it at a temperature of -20 degrees Celsius for a period of one year. It is important to avoid exposing it to repeated cycles of freezing and thawing. By following these guidelines, you can ensure that the product maintains its efficacy and performance over time.
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity).

Tissue specificityWidely expressed with highest levels in kidney, liver and placenta.
Celluar localizationEndoplasmic reticulum;Extracellular region or secreted;
UniPortQ9UNW1


Western blot analysis of extracts from 293 cells, using MINPP1 antibody.


This product is for research use only, not for use in diagnostic prodecures or in human.


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