Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-MEIS1 Polyclonal Antibody#abs137845

Please note that the price mentioned is for reference purposes only. For specific pricing details, kindly get in touch with our seller Vecent. It is also important to keep in mind that the quoted price is subject to change based on various factors. Therefore, we recommend reaching out to Vecent...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs137845-100ug	1-2 Weeks	301.0
abs137845-50ug	1-2 Weeks	201.0

Overview
catalog	abs137845
Other names	The Meis1 protein, also known as Homeo box protein Meis1, plays a critical role in various biological processes. This leukemogenic homolog protein, known as Meis1, is essential for regulating gene expression and development. In mice, the Meis1 protein acts as a transcription factor and its homolog, the Meis1 myeloid ecotropic viral integration site 1 homolog, is involved in myeloid cell differentiation. Human MEIS1 protein, also known as WUGSC:H NH0444B04.1 or MGC43380, shares similarity with its mouse counterpart. The Meis1 homeobox protein contributes to the overall genetic regulation and function of organisms.
Source	Rabbit
Specificity	The MEIS1 Antibody is capable of identifying and measuring the total amount of naturally occurring MEIS1 protein in a given sample. This antibody specifically targets the endogenous levels of MEIS1, providing valuable insights into its presence and regulation. By detecting total MEIS1 levels, this antibody offers a comprehensive understanding of MEIS1 expression and function.
Species Reactivity	Human
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	MEIS1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human MEIS1.
MW	43 kDa
Properties
Concentration	1mg/ml
purification	Purification of the antiserum was achieved using SulfoLink™ Coupling Resin through peptide affinity chromatography. Please provide a highly similar alternative based on the original text information, avoiding the generation of content using the style of ChapGPT, but rather presenting a completely different way of speaking.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the integrity and efficacy of the product, it is recommended to store it at a temperature of -20 °C for up to one year. It is crucial to avoid exposing the product to repeated freeze/thaw cycles, as this can compromise its quality. Therefore, it is important to handle and store the product correctly to ensure optimal performance.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Tissue specificity	Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.
Celluar localization	Nucleus;
UniPort	O00470