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Rabbit Anti-LRRK1 Polyclonal Antibody#abs138354

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis LRRK1 using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs138354-100ug	1-2 Weeks	301.0
abs138354-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs138354
Other names	Leucine rich repeat serine/threonine protein kinase 1, also known as LRRK1 or RIPK6, is a serine/threonine-protein kinase that is rich in leucine repeat sequences. This protein is encoded by the KIAA1790 gene and plays a crucial role in cell signaling, particularly in the regulation of immune responses and apoptosis. The LRRK1 gene has been linked to several diseases, including cancer, Alzheimer's disease, and Parkinson's disease. As an Roco protein family member, LRRK1 shares structural similarities with the ROCO proteins and may play a role in regulating signaling pathways in cells. It is a promising therapeutic target for various diseases due to its diverse biological functions and molecular mechanisms.
Source	Rabbit
Specificity	The LRRK1 Antibody is capable of detecting the total amount of endogenous LRRK1 present within the sample. The content can be rephrased by saying that the anti-LRRK1 antibody has the ability to bind with endogenous quantities of LRRK1 protein to determine its total presence.
Species Reactivity	Human;Mouse
Antigen	LRRK1
Application	Here are some different ways to express the same information: - The recommended dilution for Western blotting is between 1:1000 and 1:3000, while for immunohistochemistry it is 1:200. For ELISA assays using a peptide, the suggested dilution range is 1:20000 to 1:40000. - To achieve optimal results, we suggest using a dilution of 1:1000 to 1:3000 for Western blot analysis, 1:200 for immunohistochemistry, and 1:20000 to 1:40000 for ELISA assays with peptides. - For Western blotting, it is advisable to dilute your sample between 1:1000 and 1:3000, and for immunohistochemistry, use a 1:200 dilution. If you are performing an ELISA assay with a peptide, we recommend diluting it between 1:20000 and 1:40000. - Depending on the type of experiment you are performing, different dilutions may be necessary. For Western blotting, we recommend using a dilution range of 1:1000 to 1:3000, for immunohistochemistry a dilution of 1:200 is appropriate, and for ELISA assays using a peptide, a dilution of 1:20000 to 1:40000 should be used.
Immunogen	A synthesized peptide derived from human LRRK1.
MW	227 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the temperature remains at -20 °C during storage for a duration of one year. It is important to avoid subjecting the stored material to repetitive freeze/thaw cycles throughout this period.
Storage buffer	This buffer solution contains rabbit IgG in a phosphate buffered saline at a pH of 7.4, and is supplemented with 150mM NaCl, 0.02% sodium azide and 50% glycerol. It should be stored at a temperature of -20 °C for optimal stability, with a shelf life of 12 months from the date of receipt.
Target
Background	ATP + a protein = ADP + a phosphoprotein.
Celluar localization	Cytosol;Mitochondrion;
UniPort	Q38SD2