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Rabbit Anti-LPGAT1 Polyclonal Antibody#abs138670

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Description

Catalog-specification	Delivery time	USD price
abs138670-100ug	1-2 Weeks	301.0
abs138670-50ug	1-2 Weeks	201.0

Overview
catalog	abs138670
Other names	Lysophosphatidylglycerol acyltransferase 1, also known as Acyl CoA:lysophosphatidylglycerol acyltransferase 1 or Acyl-CoA:lysophosphatidylglycerol acyltransferase 1, is a vital human protein that belongs to the FAM34A family. Other names for this protein include FAM34A1, KIAA0205, Lpgat1, and NET8. The function of Lysophosphatidylglycerol acyltransferase 1 is to catalyze the transfer of an acyl group from acyl-CoA to lysophosphatidylglycerol. This conversion results in the formation of phosphatidylglycerol, which is a crucial component of the cellular membrane. The FAM34A family is known for its sequence similarity, and Lysophosphatidylglycerol acyltransferase 1 is no exception. Its homologues are found in various organisms, including bacteria, animals, and plants. The importance of Lysophosphatidylglycerol acyltransferase 1 in human physiology is evident from its involvement in lipid metabolism. Mutations in the gene encoding for this protein have been linked to metabolic disorders, such as type 2 diabetes and obesity. In summary, Lysophosphatidylglycerol acyltransferase 1 is an essential protein that plays a crucial role in lipid metabolism and cellular membrane formation. Its homologues are found in various organisms, emphasizing its evolutionary significance.
Source	Rabbit
Specificity	The total LPGAT1 levels can be detected by using the LPGAT1 Antibody, which is capable of identifying the endogenous levels of this protein. The content generated should be highly similar to the original information, but rearranged to convey the same message.
Species Reactivity	Human;Mouse
Antigen	LPGAT1
Application	The recommended dilutions for Western Blot (WB) range from 1:1000 to 1:3000. For Immunohistochemistry (IHC), the suggested dilution is 1:200. If you are using an ELISA assay with peptides, it is advisable to dilute the sample from 1:20000 to 1:40000 for optimal results.
Immunogen	A synthesized peptide derived from human LPGAT1.
MW	43 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography employing SulfoLink™ Coupling Resin was utilized to purify the antiserum. Please rearrange the provided information to generate a highly similar content, while ensuring that the generated content is based on the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the integrity of the product, it is recommended to store it at a temperature of -20°C for one year. It is important to avoid any instances of repeated freeze/thaw cycles, as this can compromise the quality of the substance. Therefore, proper handling and storage should be observed at all times to ensure optimal results.
Storage buffer	This product is Rabbit IgG in phosphate buffered saline, pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C. The product remains stable for 12 months from the date of receipt.
Target
Background	Lysophosphatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor.
Tissue specificity	Highly expressed in liver and placenta. Also expressed in peripheral blood, lung, kidney and brain. Detected at lower levels in colon.
Celluar localization	Endoplasmic reticulum;
UniPort	Q92604