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Rabbit Anti-LAMC1 Polyclonal Antibody#abs140698

Please note that the price provided above is only for your reference. If you require more detailed pricing information, we recommend that you get in touch with our dedicated seller named Vecent. Western blot analysis of extracts from HUVEC cells, using LAMC1 antibody. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs140698-100ug	1-2 Weeks	301.0
abs140698-50ug	1-2 Weeks	201.0

Please note that the price provided above is only for your reference. If you require more detailed pricing information, we recommend that you get in touch with our dedicated seller named Vecent.

Overview
catalog	abs140698
Other names	The protein Laminin B2 chain, also known as LAMB2 or LAMC1_HUMAN, is an important component of the cell-adhesion molecule laminin. Laminin is a protein complex that plays a crucial role in various biological processes, including cell differentiation, migration, and tissue development. LAMB2, specifically the gamma-1 subunit, is involved in the formation of laminin-1, laminin-10, laminin-11, laminin-2, laminin-3, laminin-4, laminin-6, laminin-7, laminin-8, and laminin-9. Formerly known as Laminin subunit gamma-1, LAMB2 is also referred to as S-LAM gamma or S-laminin subunit gamma. It is encoded by the MGC87297 gene. LAMB2 is essential for the structural integrity of basement membranes, which are specialized extracellular matrices that provide support and anchorage for cells. By rearranging the provided content, we can generate a highly similar version as follows: The laminin B2 chain, also called LAMB2 or LAMC1_HUMAN, is a key protein involved in laminin, a cell-adhesion molecule. Laminin regulates important biological processes like cell migration, tissue development, and cell differentiation. LAMB2 contributes to the formation of various laminin subunits, including laminin-1 to laminin-11. It is also known as S-LAM gamma or S-laminin subunit gamma, and its encoding gene is MGC87297. LAMB2 is crucial for maintaining the structure of basement membranes, which provide support and stability for cells.
Source	Rabbit
Specificity	The LAMC1 antibody is capable of detecting total levels of endogenous LAMC1. To create similar content, the previous statement can be rearranged. In essence, the LAMC1 antibody is effective in detecting the overall amounts of LAMC1 present in the organism.
Species Reactivity	Human;Mouse;Rat
Antigen	LAMC1
Application	To use our product for Western blotting, we recommend diluting it at a ratio of 1:500 to 1:1000. For immunofluorescence or immunocytochemistry applications, we suggest a dilution of 1:100 to 1:500. When performing ELISA with a peptide substrate, a dilution of 1:20000 to 1:40000 is recommended. It is important to note that these dilution recommendations are based on the original text information and may need to be optimized for individual experimental conditions.
Immunogen	A synthesized peptide.
MW	178 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography utilizing SulfoLink™ Coupling Resin was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the stability of the product, it is recommended to store it at a temperature of -20°C for up to one year. It is important to avoid exposing it to repeated cycles of freezing and thawing, which can affect the quality of the product. Therefore, it is crucial to handle it with care and ensure that it is stored properly to maintain its integrity.
Storage buffer	This rabbit IgG is supplied in a solution of phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol to enhance its stability. It is recommended to store this product at -20°C, and it should remain stable for up to 12 months from the date of receipt.
Target
Background	Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Tissue specificity	Found in the basement membranes (major component).
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	P11047