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Rabbit Anti-IQGAP3 Polyclonal Antibody#abs134691

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Description

Catalog-specification	Delivery time	USD price
abs134691-100ug	1-2 Weeks	301.0
abs134691-50ug	1-2 Weeks	201.0

Overview
catalog	abs134691
Other names	IQ motif containing GTPase activating protein 3, also known as IQGAP3 or Ras GTPase-activating-like protein IQGAP3, is a human gene that encodes a protein involved in regulating various cellular processes, including cell adhesion and migration, cell division, and signaling pathways. IQGAP3 contains several IQ motifs, which are known to mediate binding to calmodulin and other calcium-binding proteins. The protein also contains a GTPase-activating protein (GAP) domain, which is involved in regulating the activity of small GTPases such as Ras and Rho. IQGAP3 has been implicated in various diseases, including cancer and neurological disorders, and is therefore considered a potential therapeutic target. Despite its functional importance, much remains to be learned about the precise mechanisms by which IQGAP3 regulates cellular processes and how it contributes to disease.
Source	Rabbit
Specificity	The total IQGAP3 protein levels can be detected by using the IQGAP3 antibody, which specifically targets the endogenous levels of IQGAP3.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	IQGAP3
Application	The recommended dilution for Western blot (WB) is typically between 1:500 to 1:1000. For immunofluorescence (IF) or immunocytochemistry (ICC) experiments, the suggested dilution range is 1:100 to 1:500. When performing ELISA using peptides, the optimal dilution ranges from 1:20000 to 1:40000. It is important to follow these dilution guidelines to obtain accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	180 KD
Properties
Concentration	1mg/ml
purification	By employing SulfoLink™ Coupling Resin, we successfully carried out peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to store this product at a temperature of -20 °C for a period of one year. However, it is important to avoid subjecting the product to repeated freeze and thaw cycles, as this may impact its quality and efficacy. Keep this in mind when handling and storing the product to ensure optimal long-term storage and use.
Storage buffer	This product contains Rabbit IgG in a buffered saline solution with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to be stored at -20 °C and can be kept for up to 12 months from the date of receipt.
Target
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q86VI3