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Rabbit Anti-GRTP1 Polyclonal Antibody#abs141173

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Description

Catalog-specification	Delivery time	USD price
abs141173-100ug	1-2 Weeks	301.0
abs141173-50ug	1-2 Weeks	201.0

Overview
catalog	abs141173
Other names	Growth hormone-regulated TBC protein 1, also known as Grtp1 or TBC1D6, is a protein that plays a role in growth hormone regulation. It is encoded by the FLJ22474 gene, and other aliases for this gene include GRTP1_HUMAN, MGC138328, MGC138330, and OTTHUMP00000018752. TBC1D6 belongs to the TBC1 domain family, specifically TBC1 domain family member 6. This protein is involved in various cellular processes and signaling pathways. It has been shown to regulate the activity of RAB GTPases, which are essential for intracellular trafficking and vesicle fusion. Some studies have suggested that TBC1D6 may be involved in the regulation of insulin-stimulated glucose transporter GLUT4 trafficking in adipocytes. Understanding the function and regulation of TBC1D6 can provide valuable insights into the mechanisms of growth hormone signaling and cellular trafficking pathways. Further research is needed to fully unravel the role of TBC1D6 and its potential implications in various physiological and pathological conditions.
Source	Rabbit
Specificity	The detection of total GRTP1, at its endogenous levels, can be achieved using the GRTP1 Antibody. To generate highly similar content, one could rephrase the original text as follows: "Endogenous levels of total GRTP1 can be effectively detected by means of the GRTP1 Antibody."
Species Reactivity	Human
Antigen	GRTP1
Application	The dilution ranges for Western blot (WB) are 1:500 to 1:1000, for immunofluorescence/immunocytochemistry (IF/ICC) are 1:100 to 1:500, and for ELISA (peptide) are 1:20000 to 1:40000. It is important to note that the dilution factors mentioned are specific to the respective assays. These dilution ranges are commonly used to achieve optimal results and reduce background noise while detecting the target proteins or peptides.
Immunogen	A synthesized peptide.
MW	35 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum. This process resulted in the isolation of a highly purified antiserum with increased specificity and potency.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality and effectiveness of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It is also advisable to avoid subjecting the product to repeated cycles of freezing and thawing, as this may compromise its performance. It is important to follow these guidelines to ensure the product's optimal shelf life and efficacy.
Storage buffer	This product is Rabbit IgG, which is supplied in phosphate buffered saline at pH 7.4. It contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at -20 °C. It is stable for a period of 12 months starting from the date of receipt.
Target
Background	May act as a GTPase-activating protein for Rab family protein(s).
UniPort	Q5TC63