Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-GPR75 Polyclonal Antibody#abs133140

Please contact our seller Vecent for the detailed price as the mentioned price is just for reference. Thank you for your attention. Western blot analysis of GPR75 expression in A431 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. This product is for research...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs133140-50ug	1-2 Weeks	201.0
abs133140-100ug	1-2 Weeks	301.0

Please contact our seller Vecent for the detailed price as the mentioned price is just for reference. Thank you for your attention.

Overview
catalog	abs133140
Description	Orphan receptor;
Other names	The G protein coupled receptor 75, also known as GPR chr2 or Gpr75, is a probable G protein coupled receptor located on chromosome 2 in humans. It is also identified as GPR75_HUMAN, OTTHUMP00000159608, Probable G protein coupled receptor 75, Probable G-protein coupled receptor 75, WI 31133 or WI31133. This receptor plays a significant role in various cellular functions and signaling pathways. Understanding its function and mechanism of action could help in developing novel therapeutic targets for various diseases.
Source	Rabbit
Specificity	The GPR75 antibody is capable of detecting total GPR75 levels that are naturally occurring within the body. This means that it can be used to monitor the amount of GPR75 protein that is present in various tissues and cell types. By using this antibody, researchers can gain important insights into the role that GPR75 plays in cellular processes and disease pathology. Overall, the GPR75 antibody is a valuable tool for studying this important protein and its function in the body.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit
Antigen	GPR75
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	59 kDa
Properties
Concentration	1mg/ml
purification	The purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography. Through this process, impurities were removed, and a highly purified antiserum was obtained.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for one year. It is important to avoid subjecting the product to repeated freeze and thaw cycles, as this can have an adverse effect on its properties and performance. By following these guidelines, you can ensure that the product is kept in optimal condition for its intended use.
Storage buffer	IgGpH 7.4，150mMNaCl、0.02%50%。，，。
Target
Background	G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Tissue specificity	Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer. Also expressed by islet cells (at protein level).
Celluar localization	Plasma Membrane;
UniPort	O95800