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Rabbit Anti-FGF9 Polyclonal Antibody#abs139052

Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent. Western blot analysis FGF9 using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs139052-100ug	1-2 Weeks	301.0
abs139052-50ug	1-2 Weeks	201.0

Please note that the price provided is for your reference only. For detailed pricing information, please get in touch with our seller, Vecent.

Overview
catalog	abs139052
Other names	Fibroblast growth factor 9, also known as FGF-9 or FGF9, is a protein that plays a crucial role in various biological processes. It is encoded by the FGF9 gene in humans. FGF-9 is also referred to as glia-activating factor (GAF) due to its ability to stimulate glial cell activity in the nervous system. Another name for FGF-9 is heparin-binding growth factor 9, or HBFG-9, which highlights its affinity for binding to heparin molecules. It is worth mentioning that FGF-9 is closely related to the regulation of glial cell function and development. In terms of molecular biology, FGF-9 is composed of a sequence of amino acids that define its primary structure. It is a signaling protein that belongs to the fibroblast growth factor family, which consists of numerous growth factors involved in cellular growth and regeneration processes. FGF-9 is involved in various physiological processes such as embryonic development, tissue repair, and angiogenesis. It acts by binding to specific receptors on the cell surface, initiating a signaling cascade inside the cell that leads to various cellular responses. The binding of FGF-9 to its receptors triggers the activation of several intracellular pathways, including the mitogen-activated protein kinase (MAPK) pathway, which is crucial for cell proliferation and survival. Studies have shown that FGF-9 plays a critical role in the development of various tissues and organs, including the lung, heart, and brain. It is involved in the regulation of cell proliferation, migration, and differentiation, and abnormalities in FGF-9 signaling have been associated with several diseases and developmental disorders. In conclusion, FGF-9 is a multifunctional protein that plays an important role in various physiological processes. Its ability to activate glial cells in the nervous system and its involvement in tissue development make it an essential factor for proper biological functioning.
Source	Rabbit
Specificity	The total FGF9 levels can be detected by the FGF9 Antibody, which is capable of identifying endogenous levels of FGF9. Let's create content in a highly similar manner by rearranging the above information: The FGF9 Antibody is effective in detecting the endogenous levels of total FGF9. It specifically recognizes and identifies the presence of FGF9 protein.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog;Horse;
Antigen	FGF9
Application	The recommended dilutions for Western blotting range from 1:1000 to 1:3000, while for immunohistochemistry it is 1:200. For ELISA using peptides, the suggested dilutions are between 1:20000 to 1:40000. It is important to note that these dilutions are based on the original text information and changing them may affect the accuracy and specificity of the experiment. Therefore, it is recommended to adhere strictly to the dilution instructions provided for each application.
Immunogen	A synthesized peptide derived from human FGF9.
MW	23 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized in purifying the antiserum through peptide affinity chromatography. Please generate a comparable paragraph by rearranging the provided content while preserving the original information.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality, it is recommended to store at a temperature of -20 °C for a duration of one year. It is important to prevent the occurrence of repeated cycles of freezing and thawing.
Storage buffer	This solution contains Rabbit IgG in a phosphate buffered saline solution with a pH of 7.4, 150mM NaCl, and 0.02% sodium azide. Additionally, it has 50% glycerol for preservation and should be kept at a temperature of -20°C. This solution is stable for up to 12 months from its date of receipt.
Target
Background	Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.
Tissue specificity	Glial cells.
Posttranslational modification	Three molecular species were found (30 kDa, 29 kDa and 25 kDa), cleaved at Leu-4, Val-13 and Ser-34 respectively. The smaller ones might be products of proteolytic digestion. Furthermore, there may be a functional signal sequence in the 30 kDa species which is uncleavable in the secretion step.N-glycosylated.
Celluar localization	Extracellular region or secreted;
UniPort	P31371