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Rabbit Anti-FDCSP Polyclonal Antibody#abs139707

Attention: Our seller Vecent will provide you with the detailed price. The price mentioned above is only for reference. Please get in touch with Vecent for accurate pricing information. Western blot analysis FDCSP using HepG2 whole cell lysates This product is for research use only, not for use...

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Description

Catalog-specification	Delivery time	USD price
abs139707-100ug	1-2 Weeks	301.0
abs139707-50ug	1-2 Weeks	201.0

Attention: Our seller Vecent will provide you with the detailed price. The price mentioned above is only for reference. Please get in touch with Vecent for accurate pricing information.

Overview
catalog	abs139707
Other names	Follicular dendritic cell secreted peptide (FDC-SP), also known as C4orf7, is a protein that is secreted by follicular dendritic cells (FDCs). FDCs are a type of cell found in lymphoid tissues, such as lymph nodes and the spleen, and they play a critical role in the immune response. FDC-SP is a highly conserved protein that is involved in the regulation of immune cell function. It is thought to play a role in the development and maintenance of FDC networks, which are essential for the formation and maturation of B cell follicles. The exact function of FDC-SP is still not fully understood, but it is believed to be involved in the interaction between FDCs and B cells. FDCs capture antigens and present them to B cells, which helps to initiate and regulate the production of antibodies. Studies have also suggested that FDC-SP may have potential as a biomarker for certain diseases, such as autoimmune disorders and certain types of cancer. Further research is needed to fully understand the role of FDC-SP in these conditions. In conclusion, FDC-SP is a secreted protein that is produced by follicular dendritic cells and is involved in the regulation of immune cell function. Its exact role and potential as a biomarker for disease are areas that require further investigation.
Source	Rabbit
Specificity	Total FDCSP can be detected by the FDCSP Antibody, which specifically targets endogenous levels of the protein. To reiterate, the antibody is capable of accurately recognizing and measuring total FDCSP present in biological samples.
Species Reactivity	Human
Antigen	FDCSP
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human FDCSP.
MW	10 kDa
Properties
Concentration	1mg/ml
purification	The purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store the product at a temperature of -20 °C for a duration of one year. It is crucial to prevent the product from undergoing multiple cycles of freezing and thawing.
Storage buffer	This product is Rabbit IgG that has been formulated in a solution containing phosphate buffered saline with a pH of 7.4 and 150mM NaCl. It also includes 0.02% sodium azide and 50% glycerol for stability. Storage is recommended at a temperature of -20 °C, and the product is guaranteed to remain stable for 12 months from the date of receipt.
Target
Background	A secreted mediator that selectively binds to the surface of B-lymphoma cells, but not T-lymphoma cells, is known to have the ability to interact with B-cells specifically. This suggests that its function is confined to acting upon B-cells.
Tissue specificity	Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon.
Posttranslational modification	O-glycosylated with core 1 or possibly core 8 glycans.
Celluar localization	Extracellular region or secreted;
UniPort	Q8NFU4