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Rabbit Anti-MESDC2 Polyclonal Antibody#abs137448

Please note that the price mentioned above is only for your reference. For specific pricing details, kindly reach out to our seller, Vecent. Western blot analysis MESDC2 using NIH-3T3 whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs137448-100ug	1-2 Weeks	301.0
abs137448-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For specific pricing details, kindly reach out to our seller, Vecent.

Overview
catalog	abs137448
Other names	Mesoderm development protein (MESD), also known as KIAA0081, is an important chaperone for the LDL receptor (LDLR). It plays a crucial role in renal carcinoma antigen NY REN 61 and has been identified as a potential target for the treatment of renal cancer. Additionally, MESD has been designated as MESDC 2, indicating its significance in mesoderm development. Its function as a chaperone for LDLR suggests its involvement in lipid metabolism and cardiovascular health. The precise mechanisms and molecular pathways associated with MESD and its various roles are still being explored, but its potential therapeutic applications make it an intriguing protein for further investigation.
Source	Rabbit
Specificity	Total MESDC2 can be detected by the MESDC2 Antibody at its endogenous levels.
Species Reactivity	Human
Predictive reaction species	Zebrafish;Chicken;Bovine
Antigen	MESDC2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human MESDC2.
MW	26 kDa
Properties
Concentration	1mg/ml
purification	The SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve its quality, keep the store at a temperature of -20 °C for a duration of one year. Make sure to prevent repeated freezing and thawing cycles.
Storage buffer	Please note the following instructions for the storage and stability of Rabbit IgG in the provided solution. The Rabbit IgG should be kept in phosphate buffered saline with a pH of 7.4. It is important to maintain a concentration of 150mM NaCl and include 0.02% sodium azide and 50% glycerol. The appropriate storage temperature is -20 °C. It is essential to adhere to these storage conditions to ensure the stability of the Rabbit IgG for a period of 12 months from the date of receipt.
Target
Background	Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Celluar localization	Endoplasmic reticulum;Plasma Membrane;
UniPort	Q14696