Rabbit Anti-ERGI3 Polyclonal Antibody #abs130504

abs130504-50ug

1-2 Weeks

201

abs130504-100ug

1-2 Weeks

301

Other names

ERGI3, also known as Endoplasmic reticulum-Golgi intermediate compartment protein 3 or ERp43, is a protein located in the endoplasmic reticulum and Golgi intermediate compartment. It is encoded by the gene 2310015B14Rik and is also referred to as AV318804, C20orf47, CGI 54, D2Ucla1, dJ477O4.2, DKFZp547A2190, Endoplasmic reticulum localized protein, ERV46, NY BR 84, PRO0989, RP23-220D12.2, RP3-477O4.1, SDBCAG84 or Serologically defined breast cancer antigen 84.
ERGI3 plays a crucial role in protein processing and trafficking between the endoplasmic reticulum and Golgi apparatus. It is involved in the quality control of newly synthesized glycoproteins and regulates their transport from the endoplasmic reticulum to the Golgi for further modifications. Dysfunction of ERGI3 has been linked to various diseases, including cancer and neurodegenerative disorders.
In conclusion, ERGI3 is a vital protein that performs essential functions in protein processing and trafficking within the cell. Its role in various diseases highlights its significance in maintaining cellular homeostasis and underscores the need for further research on its mechanisms of action.

Source

Rabbit

Specificity

ERGI3 Antibody detects endogenous levels of ERGI3.

Species Reactivity

Human;Mouse

Predictive reaction species

Pig;Rabbit;Sheep;Dog;Bovine;Horse;

Application

Our recommended dilution for western blotting is between 1:500-1:2000, while for immunofluorescence/immunocytochemistry, we suggest a range of 1:100-1:500. If you are performing ELISA with peptide, we suggest a dilution range of 1:20000-1:40000. These dilution ranges are based on the original information provided and have been proven effective in previous experiments. Please adjust accordingly based on your specific experimental conditions.

Immunogen

A synthesized peptide derived from human ERGI3.

Properties

Concentration

1mg/ml

Purification

The SulfoLink™ Coupling Resin was utilized for peptide affinity chromatography in order to purify the antiserum.

Clonality

Polyclonal Antibody

Stability & Storage

To maintain the integrity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid any repetitive and frequent cycles of freezing and thawing. This will help preserve the quality and effectiveness of the product.

Storage buffer

The rabbit IgG is stored in a solution containing phosphate buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C. The stability of the IgG is guaranteed for a period of 12 months from the date it is received.

Target

Background

One potential function in cellular transportation could be facilitating the movement of molecules between the endoplasmic reticulum and Golgi apparatus. This role involves ensuring efficient and accurate transport of proteins and lipids along the secretory pathway. By assisting with transport, this process helps maintain the proper functioning and organization of the cell's organelles.

Celluar localization

Endoplasmic reticulum;Golgi apparatus;

UniPort

Q9Y282